NCT02958215 is a Phase 2 clinical trial of Phenylephrine in Anesthesia, Obstetrical, sponsored by Assiut University.

Who is sponsoring NCT02958215?

NCT02958215 is sponsored by Assiut University.

What drugs are being tested in NCT02958215?

Interventions in NCT02958215: Phenylephrine, Placebo.

What condition does NCT02958215 study?

NCT02958215 studies Anesthesia, Obstetrical, Anesthesia, Spinal.

Is NCT02958215 still recruiting?

NCT02958215 is currently completed. Last updated 16 May 2017.

Last reviewed 2017-05-16 · How we verify

NCT02958215

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Study Evaluating Hypotension and Autonomic Nervous System Dysfunction During Spinal Anesthesia for Cesarean Section and Its Relation to the Effect of Prophylaxis Phenylephrine

Completed Phase 2 Last updated 16 May 2017

What this trial tests

Phase 2 trial testing Phenylephrine in Anesthesia, Obstetrical in 980 participants. Completed in 1 May 2017.

Timeline

1 June 2016

Primary endpoint
1 May 2017

1 May 2017

Quick facts

Lead sponsor	Assiut University
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	980
Start date	1 June 2016
Primary completion	1 May 2017
Estimated completion	1 May 2017
Sites	1 location across Egypt

Drugs / interventions tested

Phenylephrine (phenylephrine) — full drug profile →
Placebo

Conditions studied

Anesthesia, Obstetrical — all drugs for Anesthesia, Obstetrical →
Anesthesia, Spinal — all drugs for Anesthesia, Spinal →

Sponsor

Assiut University

Who can join

Adults 18 to 50, female only, with Anesthesia, Obstetrical or Anesthesia, Spinal. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Incidence of hypotension
Time frame: within first 24 hours after spinal anesthesia
blood pressure will be measured every 3 minutes within the first 30 minutes after spinal block the every 5 minutes till the end of the caesarian section. postoperatively will be checked every 15 minutes in the first hour the every 30 minutes till the recovery from spinal block

Sponsor's own description

Pregnant women with a positive preoperative Supine stress test were found to be a subgroup at increased risk of symptomatic hypotension after spinal anesthesia

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Phenylephrine

Trials testing the same drug.

NCT06648850 — Clinical Study of DA-001 as a Treatment for Hair Shedding Reduction and Hair Re-Growth · Phase 2, PHASE3 · not yet recruiting
NCT06158035 — ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment in Preeclamptic Patients · NA · unknown
NCT07033845 — Pharmacokinetic Study of Topical Phenylephrine · EARLY_PHASE1 · recruiting
NCT06158009 — ED90 of Norepinephrine and Phenylephrine Boluses Under Intensive Treatment · NA · unknown
NCT06508359 — Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension. · NA · not yet recruiting

Other recruiting trials for Anesthesia, Obstetrical

Currently open trials in the same condition.

NCT03167905 — CODEPAD (Collaborative Outcomes of DEpression and Pain Associated With Delivery) · Phase 2, PHASE3 · active not recruiting

Other Assiut University trials

Trials by the same sponsor.

NCT07423312 — Lead Exposure and Multiple Sclerosis · not yet recruiting
NCT07234526 — Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients · not yet recruiting
NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02958215 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Assiut University
Last refreshed: 16 May 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02958215.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing