NCT02957786 (RAUORA) is a Phase 3 clinical trial of Cytisine in Smoking Cessation, sponsored by University of Auckland, New Zealand.

Who is sponsoring NCT02957786?

NCT02957786 is sponsored by University of Auckland, New Zealand.

What drugs are being tested in NCT02957786?

Interventions in NCT02957786: Cytisine, Behavioural support, Varenicline.

What condition does NCT02957786 study?

NCT02957786 studies Smoking Cessation.

Is NCT02957786 still recruiting?

NCT02957786 is currently completed. Last updated 19 August 2021.

Last reviewed 2021-08-19 · How we verify

NCT02957786: RAUORA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cytisine Versus Varenicline for Smoking Cessation

Completed Phase 3 Last updated 19 August 2021

What this trial tests

Phase 3 trial testing Cytisine in Smoking Cessation in 679 participants. Completed in 10 October 2019.

Timeline

18 September 2017

Primary endpoint
10 October 2019

10 October 2019

Quick facts

Lead sponsor	University of Auckland, New Zealand
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	679
Start date	18 September 2017
Primary completion	10 October 2019
Estimated completion	10 October 2019
Sites	1 location across New Zealand

Drugs / interventions tested

Cytisine (cytisine) — full drug profile →
Behavioural support
Varenicline (varenicline) — full drug profile →

Conditions studied

Smoking Cessation — all drugs for Smoking Cessation →

Sponsor

University of Auckland, New Zealand

Who can join

18 and older, any sex, with Smoking Cessation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate the effectiveness, safety, and cost-effectiveness of cytisine plus behavioural support compared to varenicline plus behavioural support for smoking cessation, in indigenous Māori (or family of Māori) who smoke and are motivated to quit.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Cytisine versus varenicline for smoking cessation in New Zealand indigenous Māori: a randomized controlled trial.
Walker N, Smith B, Barnes J, Verbiest M, et al · · 2021 · cited 49× · PMID 33761149 · DOI 10.1111/add.15489
Cytisine versus varenicline for smoking cessation for Māori (the indigenous people of New Zealand) and their extended family: protocol for a randomized non-inferiority trial.
Walker N, Smith B, Barnes J, Verbiest M, et al · · 2019 · cited 9× · PMID 30276931 · DOI 10.1111/add.14449

Verify or expand the search:

Other trials of Cytisine

Trials testing the same drug.

NCT06832085 — Combination Nicotine Replacement Therapy, Cytisine, or Varenicline for Smoking Cessation · Phase 4 · recruiting
NCT05102123 — PeRiopEratiVE SmokiNg CessaTion Trial · Phase 3 · active not recruiting
NCT05729243 — Cytisine for Smoking Cessation · Phase 4 · completed
NCT05311085 — Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion) · Phase 3 · completed
NCT04286295 — Cytisine Compared to Combination NRT in Relapsed Smokers · NA · terminated

Other recruiting trials for Smoking Cessation

Currently open trials in the same condition.

NCT07420621 — Preliminary Effectiveness of Enhanced Text Message + Incentives · NA · recruiting
NCT07224087 — Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients · Phase 1 · recruiting
NCT07331519 — Integrating Smoking Cessation With Low-dose CT-screening for Lung Cancer · NA · recruiting
NCT07210567 — Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors · NA · recruiting
NCT07129590 — Trauma-Informed Care for Smoking Cessation for Pregnancy · NA · recruiting

Other University of Auckland, New Zealand trials

Trials by the same sponsor.

NCT06831006 — Assessing the Effect of Cool Roofs on Health Using Smartwatches in Colima, Mexico · NA · not yet recruiting
NCT07405320 — A Brief Video Intervention to Improve Patient Outcomes Following Radioiodine Treatment · NA · not yet recruiting
NCT07337343 — Co-Development and Validation of Colonic Symptom Pictograms for Young People · not yet recruiting
NCT07131709 — Patient Satisfaction With AI Scribes · NA · completed
NCT06162468 — Feasibility Trial of EUS-PCA in IPMN Pancreatic Cysts · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02957786 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Auckland, New Zealand
Last refreshed: 19 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02957786.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing