Last reviewed · How we verify
NCT02955446
Compassionate Use Protocol for PF-03084014 in Patients With Advanced Solid Tumor Malignancies
trial testing PF-03084014 in Neoplasm. No longer available.
Quick facts
| Lead sponsor | University of Colorado, Denver |
|---|---|
| Status | NO LONGER AVAILABLE |
| Study type | EXPANDED_ACCESS |
| Sites | 1 location across United States |
Drugs / interventions tested
- PF-03084014 — full drug profile →
Conditions studied
- Neoplasm — all drugs for Neoplasm →
- Desmoid Tumor — all drugs for Desmoid Tumor →
Sponsor
University of Colorado, Denver
Who can join
Adults 16 to 101, any sex, with Neoplasm or Desmoid Tumor. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single-center, open label, non randomized, compassionate use protocol in patients with advanced solid tumor malignancies who were previously enrolled in the phase I study (NCT00878189) of this agent.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Therapeutic Targeting of Notch Signaling: From Cancer to Inflammatory Disorders.
Allen F, Maillard I. · · 2021 · cited 62× · PMID 34124039 · DOI 10.3389/fcell.2021.649205
Verify or expand the search:
- PubMed search for NCT02955446
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of PF-03084014
Trials testing the same drug.
- NCT02299635 — A Study Evaluating PF-03084014 In Patients With Advanced Breast Cancer With Or Without Notch Alterations · Phase 2 · terminated
- NCT02109445 — Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarc · Phase 2 · terminated
- NCT01876251 — A Study Evaluating The PF-03084014 In Combination With Docetaxel In Patients With Advanced Breast Cancer · Phase 1 · terminated
- NCT01981551 — Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis · Phase 2 · completed
- NCT00878189 — A Trial In Patients With Advanced Cancer And Leukemia · Phase 1 · completed
Other recruiting trials for Neoplasm
Currently open trials in the same condition.
- NCT07447089 — EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study · NA · recruiting
- NCT06739655 — Preoperative Radiation Therapy and Immediate Breast Reconstruction · NA · recruiting
- NCT06813235 — Dream2Heal: An Adaptive Stepped-care Intervention for Chinese Cancer Survivors With Mild-to-moderate Insomnia · NA · recruiting
- NCT06759649 — A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies · Phase 1 · recruiting
- NCT06980012 — Evaluation of the Impact of the Clinical Pharmacist in Oral Therapies in Oncology. · NA · recruiting
Other University of Colorado, Denver trials
Trials by the same sponsor.
- NCT07292285 — The Surveillance Nonoperative Watch & Wait (SNOWW) Rectal Cancer Trial. · not yet recruiting
- NCT07021937 — Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity · Phase 3 · not yet recruiting
- NCT07453732 — Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients. · NA · not yet recruiting
- NCT07038278 — 5-AminoLevulinic Acid Aided Resection Margins in Sarcoma · EARLY_PHASE1 · not yet recruiting
- NCT07279558 — Cannabidiol and Alcohol Use Disorder Phenotypes · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02955446 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Colorado, Denver
- Last refreshed: 1 February 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02955446.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing