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NCT02947776: SUPERB
Adjustment With Aphasia After Stroke: SUPERB
NA trial testing PEER in Stroke in 62 participants. Completed in 20 August 2019.
20 August 2019
Quick facts
| Lead sponsor | City, University of London |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 62 |
| Start date | 25 May 2017 |
| Primary completion | 20 August 2019 |
| Estimated completion | 20 August 2019 |
| Sites | 5 locations across United Kingdom |
Drugs / interventions tested
- PEER
- USUAL
Conditions studied
Sponsor
City, University of London
Who can join
18 and older, any sex, with Stroke or Aphasia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Aims: This exploratory trial will: 1. Explore the feasibility of a definitive/phase III RCT on clinical and cost-effectiveness of peer-befriending for people with aphasia post-stroke. 2. Investigate psychological and social wellbeing outcomes of participants, significant others, and peer befrienders. 3. Explore the feasibility of a full economic evaluation of usual care + peer befriending versus usual care control. Design: Single blind, mixed methods, parallel group phase II RCT comparing usual care + peer-befriending vs. usual care, starting at discharge from hospital. The study will deliver on four work packages: development phase; RCT; qualitative study; economic evaluation. Participants (n=60) will be assessed three times up to 10 months post-randomisation. Outcome measures: Feasibility: feasibility of recruitment to definitive trial (proportion screened who meet criteria; proportion who consent; rate of consent); participant, significant other, peer befriender views on acceptability of procedures (qualitative study); number of missing/incomplete data on outcome measures; attrition rate at follow-up; potential value of conducting main trial using value of information analysis (economic evaluation); description of usual care; treatment fidelity of peer-befriending. Patient-reported outcomes will include mood, wellbeing, communication and social participation. Benefits: Peer befriending may help avert some of the serious psychological consequences of stroke, and prevent the need for more complex and costly psychological therapies.
Publications & conference data
7 peer-reviewed publications reference this trial (live from Europe PMC):
-
Supporting wellbeing through peer-befriending (SUPERB) for people with aphasia: A feasibility randomised controlled trial.
Hilari K, Behn N, James K, Northcott S, et al · · 2021 · cited 29× · PMID 33624514 · DOI 10.1177/0269215521995671 -
Adjustment with aphasia after stroke: study protocol for a pilot feasibility randomised controlled trial for SUpporting wellbeing through PEeR Befriending (SUPERB).
Hilari K, Behn N, Marshall J, Simpson A, et al · · 2019 · cited 16× · PMID 30693094 · DOI 10.1186/s40814-019-0397-6 -
Pharmacological, non-invasive brain stimulation and psychological interventions, and their combination, for treating depression after stroke.
Allida SM, Hsieh CF, Cox KL, Patel K, et al · · 2023 · cited 11× · PMID 37417452 · DOI 10.1002/14651858.cd003437.pub5 -
"For them and for me": a qualitative exploration of peer befrienders' experiences supporting people with aphasia in the SUPERB feasibility trial.
Northcott S, Behn N, Monnelly K, Moss B, et al · · 2022 · cited 8× · PMID 34027757 · DOI 10.1080/09638288.2021.1922520 -
"Loneliness can also kill:" a qualitative exploration of outcomes and experiences of the SUPERB peer-befriending scheme for people with aphasia and their significant others.
Moss B, Behn N, Northcott S, Monnelly K, et al · · 2022 · cited 7× · PMID 34086521 · DOI 10.1080/09638288.2021.1922519 -
SUpporting wellbeing through PEeR-Befriending (SUPERB) feasibility trial: fidelity of peer-befriending for people with aphasia.
Behn N, Moss B, McVicker S, Roper A, et al · · 2021 · cited 3× · PMID 34341046 · DOI 10.1136/bmjopen-2020-047994 -
A pilot economic evaluation of a feasibility trial for SUpporting wellbeing through PEeR-Befriending (SUPERB) for post-stroke aphasia.
Flood C, Behn N, Marshall J, Simpson A, et al · · 2022 · cited 2× · PMID 35108114 · DOI 10.1177/02692155211063554
Verify or expand the search:
- PubMed search for NCT02947776
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02947776 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by City, University of London
- Last refreshed: 22 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02947776.
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