Pilot Randomized Study of the Sidlenafil Efficacy in Combination With Oral Anticoagulants in the Treatment of Patients With Intermediate-high Risk of Pulmonary Embolism (PSCAT)

NCT02946944 Phase 1 UNKNOWN

Pilot randomized study of the sidlenafil efficacy in combination with oral anticoagulants in the treatment of patients with intermediate-high risk of pulmonary embolism

Details

Lead sponsor	Meshalkin Research Institute of Pathology of Circulation
Phase	Phase 1
Status	UNKNOWN
Enrolment	100
Start date	2016-10
Completion	2020-10

Conditions

• Pulmonary Embolism
• Intermediate-high Risk
• Combination of Oral Anticoagulation Therapy and Sildenafil

Interventions

• Sildenafil/apixaban
• apixaban

Primary outcomes

• MSCT RV \ LV Index — 7th day
  on the 7th day of treatment RV \\ LV Index (calculated according to MSCT angiography of the pulmonary arteries)

Countries

Russia