NCT02946281 (Do CHANGE) is a NA clinical trial of Do CHANGE in Lifestyle, sponsored by Elisabeth-TweeSteden Ziekenhuis.

Who is sponsoring NCT02946281?

NCT02946281 is sponsored by Elisabeth-TweeSteden Ziekenhuis.

What drugs are being tested in NCT02946281?

Interventions in NCT02946281: Do CHANGE.

Is NCT02946281 still recruiting?

NCT02946281 is currently completed. Last updated 26 July 2018.

Last reviewed 2018-07-26 · How we verify

NCT02946281: Do CHANGE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Do Cardiac Health: Advanced New Generation Ecosystem

Completed NA Last updated 26 July 2018

What this trial tests

NA trial testing Do CHANGE in Lifestyle in 149 participants. Completed in 22 December 2017.

Timeline

19 December 2016

Primary endpoint
22 December 2017

22 December 2017

Quick facts

Lead sponsor	Elisabeth-TweeSteden Ziekenhuis
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	149
Start date	19 December 2016
Primary completion	22 December 2017
Estimated completion	22 December 2017
Sites	2 locations across Netherlands, Spain

Drugs / interventions tested

Do CHANGE

Conditions studied

Lifestyle — all drugs for Lifestyle →

Sponsor

Elisabeth-TweeSteden Ziekenhuis

Who can join

Adults 18 to 75, any sex, with Lifestyle. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of Do CHANGE is to develop a health ecosystem for integrated disease management of citizens with high blood pressure and patients with ischemic heart disease or heart failure. The system will give them access to a set of personalized health services in a near real-time fashion. This disruptive system will incorporate the behaviour change methods, such as "Do Something Different", in conjunction with new innovative wearable/portable tools that can monitor behaviour and clinical parameters in normal living situations.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Enhancing Lifestyle Change in Cardiac Patients Through the Do CHANGE System ("Do Cardiac Health: Advanced New Generation Ecosystem"): Randomized Controlled Trial Protocol.
Habibović M, Broers E, Piera-Jimenez J, Wetzels M, et al · · 2018 · cited 21× · PMID 29422454 · DOI 10.2196/resprot.8406
A Personalized eHealth Intervention for Lifestyle Changes in Patients With Cardiovascular Disease: Randomized Controlled Trial.
Broers ER, Kop WJ, Denollet J, Widdershoven J, et al · · 2020 · cited 14× · PMID 32441658 · DOI 10.2196/14570
Patient Perspectives on Health Data Privacy and Management: "Where Is My Data and Whose Is It?"
Wetzels M, Broers E, Peters P, Feijs L, et al · · 2018 · cited 11× · PMID 30631347 · DOI 10.1155/2018/3838747

Verify or expand the search:

Other trials of Do CHANGE

Trials testing the same drug.

NCT03178305 — Do Cardiac Health: Advanced New Generation Ecosystem - Phase 2 · NA · unknown

Other recruiting trials for Lifestyle

Currently open trials in the same condition.

NCT07525583 — Implementation of Decade of Healthy Ageing Action Plan to Screen and Prevent Decline in Intrinsic Capacity in Elders (SP · recruiting
NCT06601478 — Development and Implementation of a Tool for the Evaluation and Monitoring of the Mediterranean Lifestyle in the Clinica · NA · recruiting
NCT05533749 — Evaluating the Effectiveness of the GILL eHealth Intervention to Improve Physical Health and Lifestyle Behaviours in Pat · NA · recruiting
NCT06611462 — STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair · NA · recruiting
NCT06241144 — Supporting Lifestyle Changes After Delivery · NA · recruiting

Other Elisabeth-TweeSteden Ziekenhuis trials

Trials by the same sponsor.

NCT03178305 — Do Cardiac Health: Advanced New Generation Ecosystem - Phase 2 · NA · unknown
NCT03099798 — Traumatic Splenic Injury and Management (SPLENIQ Study) · completed
NCT03373487 — Cognitive Rehabilitation in Brain Tumor Patients After Neurosurgery · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02946281 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Elisabeth-TweeSteden Ziekenhuis
Last refreshed: 26 July 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02946281.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing