Comparison of Immunogenicity of Adjuvanted and Non-Adjuvanted Influenza Vaccination in a Long-Term Care Population

NCT02933723 NA UNKNOWN

The study is designed to evaluated if adjuvanted vaccine elicits higher T cell and B cell responses than non-adjuvanted standard dose influenza vaccine in nursing home residents.

Details

Lead sponsor	Insight Therapeutics, LLC
Phase	NA
Status	UNKNOWN
Enrolment	200
Start date	2016-10
Completion	2021-09-01

Conditions

• Influenza

Interventions

• Blood Draw

Primary outcomes

• Change in hemagglutination inhibition (HAI) — day 0 and day 28 +/-3 days
  Fold change in antibody titers from day 0 to day 28 as determined by vaccine strain specific Hemagglutination Inhibition (HAI)
• Change in microneutralization (MN) — day 0 and day 28 +/-3 days
  Fold change in antibody titers from day 0 to day 28 as determined by vaccine strain specific microneutralization

Countries

United States