NCT02927405

Combination of Preoperative Gabapentin and TAP Blocks in Decreasing Postoperative Pain

Withdrawn Phase 4 Last updated 25 May 2021

What this trial tests

Phase 4 trial testing Gabapentin in Postoperative Pain. Withdrawn.

Timeline

4 March 2020

Primary endpoint
31 March 2020

31 March 2020

Quick facts

Lead sponsor	State University of New York - Downstate Medical Center
Phase	Phase 4
Status	Withdrawn
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Start date	4 March 2020
Primary completion	31 March 2020
Estimated completion	31 March 2020
Sites	1 location across United States

Drugs / interventions tested

• Gabapentin (Gabapentin) — full drug profile →
• TAP Block

Conditions studied

• Postoperative Pain — all drugs for Postoperative Pain →

Sponsor

State University of New York - Downstate Medical Center

Who can join

Adults 18 to 60, female only, with Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is an increasing trend on decreasing narcotic use and maximizing efficiency in the perioperative care. There are no studies that have compared a TAP block versus a TAP block plus gabapentin for laparoscopic procures.This study will investigate if taking gabapentin and receiving a TAP block decrease post-operative morphine consumption. It will be a randomized controlled, double blind study, with 130 patients between 18-60 years; that will undergo laparoscopic GYN procedures. Secondary outcomes will look at the incidence of nausea, vomiting, and VAS (verbal analog scale) scores. This combination may be helpful because gabapentin will be used to decrease visceral and central pain, and TAP block will decrease somatic pain. Performing a multimodal approach may decrease narcotic consumption, adverse effects and improve pain management.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.