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NCT02920710

ACTHAR Therapy for Central Nervous System Sarcoidosis

Withdrawn Phase 4 Last updated 20 November 2020
What this trial tests

Phase 4 trial testing Repository Corticotropin Injection in Sarcoidosis. Withdrawn.

Timeline
1 February 2019
Primary endpoint
2 November 2020
2 November 2020

Quick facts

Lead sponsorThe Cleveland Clinic
PhasePhase 4
StatusWithdrawn
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Start date1 February 2019
Primary completion2 November 2020
Estimated completion2 November 2020
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

The Cleveland Clinic

Who can join

Eligibility, any sex, with Sarcoidosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is a need for a more reliable, expeditious therapy that can be used as an alternative to glucocorticoids in severe Central Nervous System (CNS) sarcoidosis. This study aims to provide evidence for effectiveness of ACTHAR gel in CNS sarcoidosis, and provide information about its safety and tolerability

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Refractory Sarcoidosis: A Review.
    El Jammal T, Jamilloux Y, Gerfaud-Valentin M, Valeyre D, et al · · 2020 · cited 45× · PMID 32368072 · DOI 10.2147/tcrm.s192922
  2. Clinical and immunological study of Tofacitinib and Baricitinib in refractory Blau syndrome: case report and literature review.
    Álvarez-Reguera C, Prieto-Peña D, Herrero-Morant A, Sánchez-Bilbao L, et al · · 2022 · cited 14× · PMID 35510170 · DOI 10.1177/1759720x221093211

Verify or expand the search:

Other recruiting trials for Sarcoidosis

Currently open trials in the same condition.

Other The Cleveland Clinic trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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