Last reviewed · How we verify
NCT02920710
ACTHAR Therapy for Central Nervous System Sarcoidosis
Phase 4 trial testing Repository Corticotropin Injection in Sarcoidosis. Withdrawn.
2 November 2020
Quick facts
| Lead sponsor | The Cleveland Clinic |
|---|---|
| Phase | Phase 4 |
| Status | Withdrawn |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Start date | 1 February 2019 |
| Primary completion | 2 November 2020 |
| Estimated completion | 2 November 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Repository Corticotropin Injection — full drug profile →
Conditions studied
- Sarcoidosis — all drugs for Sarcoidosis →
Sponsor
The Cleveland Clinic
Who can join
Eligibility, any sex, with Sarcoidosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
There is a need for a more reliable, expeditious therapy that can be used as an alternative to glucocorticoids in severe Central Nervous System (CNS) sarcoidosis. This study aims to provide evidence for effectiveness of ACTHAR gel in CNS sarcoidosis, and provide information about its safety and tolerability
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Refractory Sarcoidosis: A Review.
El Jammal T, Jamilloux Y, Gerfaud-Valentin M, Valeyre D, et al · · 2020 · cited 45× · PMID 32368072 · DOI 10.2147/tcrm.s192922 -
Clinical and immunological study of Tofacitinib and Baricitinib in refractory Blau syndrome: case report and literature review.
Álvarez-Reguera C, Prieto-Peña D, Herrero-Morant A, Sánchez-Bilbao L, et al · · 2022 · cited 14× · PMID 35510170 · DOI 10.1177/1759720x221093211
Verify or expand the search:
- PubMed search for NCT02920710
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT06576505 — Immunological Mechanisms in Sarcoidosis · recruiting
Other The Cleveland Clinic trials
Trials by the same sponsor.
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- NCT07073963 — Virtual Patient Groups for Sarcoidosis Associated Fatigue · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02920710 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Cleveland Clinic
- Last refreshed: 20 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02920710.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing