Who is sponsoring NCT02918851?

NCT02918851 is sponsored by Stony Brook University.

What drugs are being tested in NCT02918851?

Interventions: Transfusion of 7-day stored red blood cells, Transfusion of 28-day stored red blood cells, Transfusion of 42-day stored red blood cells.

What is the status of NCT02918851?

NCT02918851 is currently COMPLETED.

Last reviewed 2021-03-16 · How we verify

VO2 Max: In Vivo Model for Functional Red Cell Testing. Can RECESS be Explained?

NCT02918851 Phase 4 COMPLETED Results posted

This is a single-center, randomized, partially blinded study to determine whether 42-day old red blood cells (RBCs) deliver oxygen as effectively as 7-day old RBCs and also to determine whether transfusion with 28-day old RBCs is non-inferior to 7-day old RBCs with respect to oxygen delivery. In this study, subjects will be randomized to be transfused with 2 units of autologous (one's own) RBCs that are either 7-, 28-, or 42-days old. Endpoints include changes in exercise duration and VO2 max (test of oxygen consumption/delivery) between groups.

Details

Lead sponsor	Stony Brook University
Phase	Phase 4
Status	COMPLETED
Enrolment	42
Start date	2017-01
Completion	2019-11-20

Conditions

Healthy

Interventions

Transfusion of 7-day stored red blood cells
Transfusion of 28-day stored red blood cells
Transfusion of 42-day stored red blood cells

Primary outcomes

Percent Change From Baseline in Maximal Oxygen Uptake (VO2 Max) After Blood Cell Transfusion — Baseline (prior to receiving blood) and Day 2 after receiving blood
Percent Change From Baseline in Maximal Oxygen Uptake (VO2 Max) on Day 2 After Blood Cell Transfusion

Countries

United States