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NCT02916810
Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment
NA trial testing Active rTMS stimulation in Schizophrenia and Related Disorders in 140 participants. Currently enrolling.
1 July 2029
Quick facts
| Lead sponsor | The University of Texas Health Science Center, Houston |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 140 |
| Start date | 1 February 2025 |
| Primary completion | 1 July 2029 |
| Estimated completion | 1 July 2029 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Active rTMS stimulation
- Sham rTMS stimulation
Conditions studied
- Schizophrenia and Related Disorders — all drugs for Schizophrenia and Related Disorders →
Sponsor
The University of Texas Health Science Center, Houston
Who can join
Adults 18 to 50, any sex, with Schizophrenia and Related Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to test the hypothesis that functionally navigated repetitive TMS stimulations to the prefrontal cortex (PFC) modulate aberrant cortical electrical activities at PFC circuitry. The TMS location of the PFC site will be individually localized by the symptom-related functional connectivity between PFC and symptom related areas (such as the auditory and language processing cortex). The investigators predict that such modulation will correct abnormal activities in patients with schizophrenia, reduce symptoms, especially auditory hallucination, and improve working memory/sustained attention performance.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT02916810
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02916810 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The University of Texas Health Science Center, Houston
- Last refreshed: 28 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02916810.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing