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NCT02916394

In Vivo IGF-1R Molecular Imaging Using [68Ga]- Labelling Anti-IGF-1R Affibody Molecule

Status unknown NA Last updated 21 February 2020
What this trial tests

NA trial testing 68Ga-NODAGA-ZIGF-1R:4:40 in Molecular Imaging in 100 participants. Status unknown.

Timeline
1 September 2018
Primary endpoint
31 December 2020
31 December 2020

Quick facts

Lead sponsorHarbin Medical University
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposediagnostic
Enrollment100
Start date1 September 2018
Primary completion31 December 2020
Estimated completion31 December 2020
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Harbin Medical University

Who can join

Adults 18 to 80, any sex, with Molecular Imaging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators developed \[68Ga\]-labelling Anti-IGF-1R Affibody Molecule as a targeted molecular imaging agent for noninvasive and repeatable detecting IGF-1R expression status.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Protein scaffolds: antibody alternatives for cancer diagnosis and therapy.
    Luo R, Liu H, Cheng Z. · · 2022 · cited 37× · PMID 35866165 · DOI 10.1039/d2cb00094f
  2. A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.
    Davis SL, Eckhardt SG, Diamond JR, Messersmith WA, et al · · 2018 · cited 8× · PMID 30139840 · DOI 10.1634/theoncologist.2018-0315

Verify or expand the search:

Other recruiting trials for Molecular Imaging

Currently open trials in the same condition.

Other Harbin Medical University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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