Who is sponsoring TARGET BP I?

TARGET BP I is sponsored by Ablative Solutions, Inc..

What condition does TARGET BP I study?

TARGET BP I studies Hypertension.

What drugs are being tested in TARGET BP I?

Interventions: Dehydrated alcohol, Peregrine System Kit (Sham Procedure).

What is the status of TARGET BP I?

TARGET BP I is currently ACTIVE_NOT_RECRUITING.

Last reviewed 2023-10-02 · How we verify

A Pivotal, Multicenter, Blinded, Sham Procedure-Controlled Trial of Renal Denervation by the Peregrine System™ Kit, in Subjects With Hypertension (TARGET BP I)

NCT02910414 Phase 3 ACTIVE_NOT_RECRUITING

The TARGET BP I Trial is a randomized, blinded, multi-center, international, sham-procedure controlled trial, comparing renal denervation performed with the Peregrine System Kit in the treatment group to the sham control group (without renal denervation - no alcohol infusion). Subjects will be randomized in a 1:1 fashion to treatment versus sham control via central randomization.

Details

Lead sponsor	Ablative Solutions, Inc.
Phase	Phase 3
Status	ACTIVE_NOT_RECRUITING
Enrolment	300
Start date	2019-07-22
Completion	2026-05

Conditions

Hypertension

Interventions

Dehydrated alcohol
Peregrine System Kit (Sham Procedure)

Primary outcomes

Change in mean systolic ABPM — 3 months
The change in mean 24-hour ambulatory SBP from baseline to 3 months post-procedure

Countries

United States