NCT02902406 is a clinical trial in Oral Cancer, sponsored by National Taiwan University Hospital.

Who is sponsoring NCT02902406?

NCT02902406 is sponsored by National Taiwan University Hospital.

What condition does NCT02902406 study?

NCT02902406 studies Oral Cancer.

Is NCT02902406 still recruiting?

NCT02902406 is currently status unknown. Last updated 15 May 2018.

Last reviewed 2018-05-15 · How we verify

NCT02902406

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Validation of DNA Methylation Biomarkers for Oral Cancer Detection-Follow up Study

Status unknown Last updated 15 May 2018

What this trial tests

trial in Oral Cancer in 300 participants. Status unknown.

Timeline

18 April 2016

Primary endpoint
17 April 2019

Quick facts

Lead sponsor	National Taiwan University Hospital
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	300
Start date	18 April 2016
Primary completion	17 April 2019
Sites	1 location across Taiwan

Conditions studied

Oral Cancer — all drugs for Oral Cancer →

Sponsor

National Taiwan University Hospital

Who can join

20 and older, any sex, with Oral Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a follow up study which aims to evaluate the correlation between several methylated genes (potential biomarkers) and oral cancers. A prospective case control trial is designed with sample size of at least 300 cases with estimated 200 subjects with precancerous lesion or oral cancer, and 100 subjects with normal oral mucosa. This study is approved by the National Taiwan University Hospital Research Ethics Committee. After signing the informed consent, all subjects will receive an intraoral examination and followed by epithelial cells collection with oral swab. The gDNA will be extracted from the oral swab collected cells and followed by bisulfite conversion procedures. Subsequently, bisulfite converted DNA will be subjected to methylated gene detection by Real-Time PCR. The methylation index (clinical sensitivity and specificity) of oral cancer related genes will be evaluated. For diagnosis confirmation, photos and biopsy specimens will be taken upon observation of abnormal lesion.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02902406 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
Last refreshed: 15 May 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02902406.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing