Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

NCT02897778 PHASE1 COMPLETED

The purpose of this study is to evaluate the effect of entinostat on heart rate and other electrocardiogram (ECG) parameters. This study will also evaluate the safety and tolerability of entinostat, as well as pharmacokinetic and pharmacodynamic parameters.

Details

Lead sponsor	Syndax Pharmaceuticals
Phase	PHASE1
Status	COMPLETED
Enrolment	30
Start date	Wed Aug 24 2016 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Mon Mar 13 2017 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Neoplasms
• Neoplasms, Glandular and Epithelial
• Neoplasms by Histologic Type
• Bronchial Neoplasms
• Lung Neoplasms
• Respiratory Tract Neoplasms
• Thoracic Neoplasms
• Digestive System Neoplasms
• Endocrine Gland Neoplasms
• Carcinoma, Non-Small-Cell Lung

Interventions

• Entinostat
• Placebo

Countries

United States