NCT02893969 (PedCARE) is a NA clinical trial of Physical Activity in Concussions, sponsored by Children's Hospital of Eastern Ontario.

Who is sponsoring NCT02893969?

NCT02893969 is sponsored by Children's Hospital of Eastern Ontario.

What drugs are being tested in NCT02893969?

Interventions in NCT02893969: Physical Activity, Rest.

What condition does NCT02893969 study?

NCT02893969 studies Concussions, Post-Concussive Symptoms.

Is NCT02893969 still recruiting?

NCT02893969 is currently completed. Last updated 29 January 2021.

Last reviewed 2021-01-29 · How we verify

NCT02893969: PedCARE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pediatric Concussion Assessment of Rest and Exertion

Completed NA Last updated 29 January 2021

What this trial tests

NA trial testing Physical Activity in Concussions in 456 participants. Completed in 25 January 2021.

Timeline

6 March 2017

Primary endpoint
25 January 2021

25 January 2021

Quick facts

Lead sponsor	Children's Hospital of Eastern Ontario
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	456
Start date	6 March 2017
Primary completion	25 January 2021
Estimated completion	25 January 2021
Sites	1 location across Canada

Drugs / interventions tested

Physical Activity
Rest

Conditions studied

Concussions — all drugs for Concussions →
Post-Concussive Symptoms — all drugs for Post-Concussive Symptoms →

Sponsor

Children's Hospital of Eastern Ontario

Who can join

Adults 10 to 18, any sex, with Concussions or Post-Concussive Symptoms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to investigate when is the best time to resume physical activity following a head injury. Two treatment plans will be studied; the first treatment plan consists of gradually reintroducing physical activity in the child's routine, starting 72 hours following the head injury. The second treatment plan involves physical and mental rest until the child as no more symptoms. Once symptom free, physical activity is gradually reintroduced in the child's routine.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Is early activity resumption after paediatric concussion safe and does it reduce symptom burden at 2 weeks post injury? The Pediatric Concussion Assessment of Rest and Exertion (PedCARE) multicentre randomised clinical trial.
Ledoux AA, Barrowman N, Bijelić V, Borghese MM, et al · · 2022 · cited 43× · PMID 34836880 · DOI 10.1136/bjsports-2021-105030
Multicentre, randomised clinical trial of paediatric concussion assessment of rest and exertion (PedCARE): a study to determine when to resume physical activities following concussion in children.
Ledoux AA, Barrowman NJ, Boutis K, Davis A, et al · · 2019 · cited 16× · PMID 28701360 · DOI 10.1136/bjsports-2017-097981
Optimal Volume of Moderate-to-Vigorous Physical Activity Postconcussion in Children and Adolescents.
Ledoux AA, Sicard V, Bijelic V, Barrowman N, et al · · 2024 · cited 8× · PMID 38363567 · DOI 10.1001/jamanetworkopen.2023.56458
Patient engagement in pediatric concussion research.
Reed N, Leeder K, Zemek R, PedCARE Research Team. · · 2018 · cited 3× · PMID 30404847 · DOI 10.1503/cmaj.180450
Nightly Sleep Duration and Symptom Burden Over 1 Month Following Pediatric Concussion.
Butterfield L, Zemek R, Borghese MM, Bijelic V, et al · · 2025 · cited 1× · PMID 40531535 · DOI 10.1001/jamanetworkopen.2025.16333

Verify or expand the search:

Other trials of Physical Activity

Trials testing the same drug.

NCT07480811 — The Effect of the DASH Diet on Clinical and Metabolic Parameters in Children With MASLD · NA · not yet recruiting
NCT07125053 — COPD Resources, Education, and Activity Designed for You Study · NA · recruiting
NCT07099040 — Community-based Multi-domain Intervention to Detect and Delay Cognitive Decline in Community-dwelling Older Adults: A Pi · NA · not yet recruiting
NCT06948500 — Effectiveness of an IVR-based Therapeutic Exercise Program With Altered Visual Feedback in Fibromyalgia Patients · NA · recruiting
NCT06822387 — Health Without Barriers/Salud Sin Barreras- Northern Colorado · NA · recruiting

Other Children's Hospital of Eastern Ontario trials

Trials by the same sponsor.

NCT06801366 — VIdeo Clips for Diagnostic Evaluation of Obstructive Sleep Apnea in Children · recruiting
NCT06816875 — Comparison of the User Experience of Four Nasal Aspirators in Infants · NA · completed
NCT06301477 — PRecisiOn Microbiome Directed ExtensiOn of Anti-TNFα Crohn's Disease ThErapy in Children: The PROMOTE Trial · NA · active not recruiting
NCT06232733 — HELP (HEalthy Lifestyles Project) for Youth With Mental Distress · NA · recruiting
NCT06065215 — Early-life MRI Biomarkers of Longer-term Respiratory Morbidity in Infants Born Extremely Preterm (EMBLEM) · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02893969 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Children's Hospital of Eastern Ontario
Last refreshed: 29 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02893969.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing