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NCT02892227: JECICA
Management of Acute Heart Failure: Contribution of Ultrasound Daily "in Bed Patient" Adjustment on Therapy With Impact Measure on re Hospital Rate During 30 Days
NA trial testing Transmitral flow estimation in Heart Failure in 250 participants. Completed in 5 June 2019.
5 June 2019
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Nīmes |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 250 |
| Start date | 15 November 2016 |
| Primary completion | 5 June 2019 |
| Estimated completion | 5 June 2019 |
| Sites | 2 locations across France |
Drugs / interventions tested
- Transmitral flow estimation
Conditions studied
- Heart Failure — all drugs for Heart Failure →
Sponsor
Centre Hospitalier Universitaire de Nīmes
Who can join
Adults 18 to 90, any sex, with Heart Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Our hypothesis: a daily bedside echocardiographic assessment, protocolized, simple and reproducible estimation of filling pressures with an evaluation of mitral inflow and the inferior vena cava, allow a more reliable estimate of the true blood volume of the patient and thus lead to a therapeutic adjustment more suitable. This therapeutic adjustment closer to patient's needs would impact fewer readmissions at 30 days and mortality, less alteration of biological parameters myocardial, kidney and liver.
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
Ultrasound imaging of congestion in heart failure: examinations beyond the heart.
Pellicori P, Platz E, Dauw J, Ter Maaten JM, et al · · 2021 · cited 136× · PMID 33118672 · DOI 10.1002/ejhf.2032 -
New perspectives and future directions in the treatment of heart failure.
Pellicori P, Khan MJI, Graham FJ, Cleland JGF. · · 2020 · cited 32× · PMID 31327116 · DOI 10.1007/s10741-019-09829-7 -
Non-Invasive Assessment of Congestion by Cardiovascular and Pulmonary Ultrasound and Biomarkers in Heart Failure.
Ilieșiu AM, Hodorogea AS, Balahura AM, Bădilă E. · · 2022 · cited 17× · PMID 35454010 · DOI 10.3390/diagnostics12040962 -
Point of Care Ultrasound (POCUS) in the Management of Heart Failure: A Narrative Review.
Naddaf N, Dianati Maleki N, Goldschmidt ME, Kalogeropoulos AP. · · 2024 · cited 7× · PMID 39064020 · DOI 10.3390/jpm14070766 -
Impact of Daily Bedside Echocardiographic Assessment on Readmissions in Acute Heart Failure: A Randomized Clinical Trial.
Ricci JE, Aguilhon S, Occean BV, Soullier C, et al · · 2022 · cited 3× · PMID 35407655 · DOI 10.3390/jcm11072047 -
Management of acute heart failure: Contribution of daily bedside echocardiographic assessment on therapy adjustment with impact measure on the 30-day readmission rate (JECICA).
Ricci JE, Kalmanovich E, Robert C, Chevallier T, et al · · 2018 · cited 1× · PMID 30364633 · DOI 10.1016/j.conctc.2018.07.006
Verify or expand the search:
- PubMed search for NCT02892227
- Europe PMC full search
- ASCO Meeting Library
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Related trials
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Other Centre Hospitalier Universitaire de Nīmes trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02892227 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Nīmes
- Last refreshed: 12 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02892227.
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