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NCT02886468: DEEP

DEpth of EPinephrine Delivery With Auto-injectors Devices

Completed NA Last updated 26 August 2021
What this trial tests

NA trial testing skin ultrasound in Anaphylactic Shock in 107 participants. Completed in 16 August 2021.

Timeline
26 August 2016
Primary endpoint
4 May 2021
16 August 2021

Quick facts

Lead sponsorCentre Hospitalier Régional Metz-Thionville
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposeother
Enrollment107
Start date26 August 2016
Primary completion4 May 2021
Estimated completion16 August 2021
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Centre Hospitalier Régional Metz-Thionville

Who can join

18 and older, any sex, with Anaphylactic Shock. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death. Although there are several causes of fatal anaphylaxis, food allergy is one of the most common. Epinephrine is recommended as the initial treatment of choice for anaphylaxis. A delay in epinephrine administration may contribute to an increased risk of death. Therefore, the World Allergy Organization recommends that, for the treatment of anaphylaxis, epinephrine solution be administered intramuscularly in the mid-anterolateral thigh. In France 3 auto-injector pens are available: Anapen®, Epipen® and Jext®. For weight\> 30 kg, the devices have a needle size respectively of 7.49 mm, 15.02 mm and 15.36 mm. For the weights between 15 and 30 kg needle size is 7.49 mm to 12.7 mm and Anapen® for Epipen® and Jext®. Several studies suggest that the needle length needle is sometim

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Frequencies and predictors of subcutaneous and intraosseous injection with 4 epinephrine autoinjector devices.
    Lefevre S, Goetz C, Hennequin L, Zevering Y, et al · · 2024 · cited 2× · PMID 38740133 · DOI 10.1016/j.anai.2024.05.002

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Other recruiting trials for Anaphylactic Shock

Currently open trials in the same condition.

Other Centre Hospitalier Régional Metz-Thionville trials

Trials by the same sponsor.

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Data sources for this page

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