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NCT02885597
Juanbi Pill Combined With Methotrexate for Rheumatoid Arthritis: Multi-center Random Controlled Clinical Trials
Phase 2/Phase 3 trial testing Juanbi pill in Juanbi Pill in 120 participants. Status unknown.
1 December 2018
Quick facts
| Lead sponsor | Cui xuejun |
|---|---|
| Phase | Phase 2/Phase 3 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 1 July 2018 |
| Primary completion | 1 December 2018 |
| Estimated completion | 1 December 2020 |
| Sites | 1 location across China |
Drugs / interventions tested
- Juanbi pill — full drug profile →
- Juanbi pill placebo
- Methotrexate — full drug profile →
Conditions studied
- Juanbi Pill — all drugs for Juanbi Pill →
- Rheumatoid Arthritis — all drugs for Rheumatoid Arthritis →
Sponsor
Cui xuejun — full company profile →
Who can join
Adults 18 to 80, any sex, with Juanbi Pill or Rheumatoid Arthritis. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Rate of ACR (American College Of Rheumatology) 50
Time frame: at 3 months -
changes of The Disease Activity Score (DAS) 28
Time frame: from baseline to 3 months -
changes of the van der Heijde modified Sharp score
Time frame: from baseline to 12 months
Sponsor's own description
The purpose of this study is to determine whether Juanbi Pill combined with methotrexate are effective in the treatment of active Rheumatoid Arthritis (RA).
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
The efficacy of the traditional Chinese medicine Juanbi pill combined with methotrexate in active rheumatoid arthritis: study protocol for a randomized controlled trial.
Wang Q, Wang YR, Jia QY, Liu L, et al · · 2018 · cited 12× · PMID 29558967 · DOI 10.1186/s13063-018-2555-1 -
Efficacy and Safety of Juan Bi Pill with Add-on Methotrexate in Active Rheumatoid Arthritis: A 48-Week, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial.
Jia QY, Wang YR, Sun DW, Mao JC, et al · · 2025 · cited 1× · PMID 39707138 · DOI 10.1007/s11655-024-3768-7 -
Efficacy and Safety of the Juan Bi Pill Combined with Methotrexate for Treating Active Rheumatoid Arthritis
Jia Q, Wang Y, Sun D, Li Q, et al · · 2022 · DOI 10.21203/rs.3.rs-1980301/v1
Verify or expand the search:
- PubMed search for NCT02885597
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Cui xuejun trials
Trials by the same sponsor.
- NCT03593837 — Efficacy and Safety of HQGZWWT Patients With Rheumatoid Arthritis · Phase 2, PHASE3 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02885597 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cui xuejun
- Last refreshed: 13 July 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02885597.
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