Who is sponsoring TOFScan?

TOFScan is sponsored by Central Hospital, Nancy, France.

What condition does TOFScan study?

TOFScan studies Curarisation, Neuromuscular Monitoring.

What drugs are being tested in TOFScan?

Interventions: Rocuronium, Neuromuscular monitoring with TOFScan® and TOF-Watch SX®.

Last reviewed 2016-08-23 · How we verify

Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®

NCT02880787 NA UNKNOWN

The purpose is to evaluate the reproducibility of neuromuscular monitoring data of recovery from neuromuscular blockade, obtained with TOFScan® and TOF-Watch SX®, in adult and pediatric population. Secondary purposes are to evaluate the reproducibility of data obtained with 2 monitors for: * the onset of clinical action of curare: suppression of the first response of train of four monitoring (T1) of 95% initial value * the duration of clinical action of curare: recovery of the first response of train of four monitoring (T1) to 25% initial value * recovery of first (T1), second (T2), third (T3) and fourth response (T4) of train of four monitoring, and recovery of T4/T1 to 40% and 60% initial value (T4/T1 0.4 and 0.6) * complete recovery from curarisation, at T4/T1=90% and T4/T1=100%.

Details

Lead sponsor	Central Hospital, Nancy, France
Phase	NA
Status	UNKNOWN
Enrolment	142
Start date	2014-11
Completion	2016-12

Conditions

Curarisation
Neuromuscular Monitoring

Interventions

Rocuronium
Neuromuscular monitoring with TOFScan® and TOF-Watch SX®

Primary outcomes

Time of recovery of the first (T1) response of train of four monitoring displayed on TOFScan and on TOF Watch SX — day 0, after induction of anesthesia
Time of recovery of the second (T2) response of train of four monitoring displayed on TOFScan and on TOF Watch SX — day 0, after induction of anesthesia
Time of recovery of the third (T3) response of train of four monitoring displayed on TOFScan and on TOF Watch SX — day 0, after induction of anesthesia
Time of recovery of the fourth (T4) response of train of four monitoring displayed on TOFScan and on TOF Watch SX — day 0, after induction of anesthesia
Time of recovery of T4/T1 of train of four monitoring at 40% of initial value displayed on TOFScan and on TOF Watch SX — day 0, after induction of anesthesia
Time of recovery of T4/T1 of train of four monitoring at 60% of initial value displayed on TOFScan and on TOF Watch SX — day 0, after induction of anesthesia

Countries

France