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NCT02873546: ALSTICO
tDCS Effect on Cognitive Functions From Patients With Alzheimer's Disease or Progressive Primary Aphasia
NA trial testing transcranial Direct Current Stimulation (tDCS) in Alzheimer's Disease in 52 participants. Status unknown.
31 January 2018
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Besancon |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 52 |
| Start date | 19 July 2013 |
| Primary completion | 31 January 2018 |
| Estimated completion | 31 July 2018 |
| Sites | 3 locations across France |
Drugs / interventions tested
- transcranial Direct Current Stimulation (tDCS)
Conditions studied
- Alzheimer's Disease — all drugs for Alzheimer's Disease →
- Progressive Primary Aphasia — all drugs for Progressive Primary Aphasia →
- Early or Mild State — all drugs for Early or Mild State →
Sponsor
Centre Hospitalier Universitaire de Besancon
Who can join
60 and older, any sex, with Alzheimer's Disease or Progressive Primary Aphasia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the effect of 10 sessions of anodal transcranial Direct Current Stimulation (tDCS - 1 mA) applied to left Cortex DorsoLateral PreFrontal (CDLPF) of Alzheimer's or Primary Progressive Aphasia (PPA) patients compared to the application of a placebo tDCS (sham procedure) on cognitive functions, which are evaluated at short term (1 week post-treatment) and mild term (3 weeks post-treatment). After unblinding, patients who received placebo treatment could be received active tDCS.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Alzheimer's disease drug development pipeline: 2019.
Cummings J, Lee G, Ritter A, Sabbagh M, et al · · 2019 · cited 485× · PMID 31334330 · DOI 10.1016/j.trci.2019.05.008 -
Alzheimer's Disease: Models and Molecular Mechanisms Informing Disease and Treatments.
Nystuen KL, McNamee SM, Akula M, Holton KM, et al · · 2024 · cited 18× · PMID 38247923 · DOI 10.3390/bioengineering11010045 -
Non-pharmacological interventions for improving language and communication in people with primary progressive aphasia.
Roheger M, Riemann S, Brauer A, McGowan E, et al · · 2024 · cited 13× · PMID 38808659 · DOI 10.1002/14651858.cd015067.pub2
Verify or expand the search:
- PubMed search for NCT02873546
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02873546 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Besancon
- Last refreshed: 13 October 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02873546.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing