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NCT02873546: ALSTICO

tDCS Effect on Cognitive Functions From Patients With Alzheimer's Disease or Progressive Primary Aphasia

Status unknown NA Last updated 13 October 2017
What this trial tests

NA trial testing transcranial Direct Current Stimulation (tDCS) in Alzheimer's Disease in 52 participants. Status unknown.

Timeline
19 July 2013
Primary endpoint
31 January 2018
31 July 2018

Quick facts

Lead sponsorCentre Hospitalier Universitaire de Besancon
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposetreatment
Enrollment52
Start date19 July 2013
Primary completion31 January 2018
Estimated completion31 July 2018
Sites3 locations across France

Drugs / interventions tested

Conditions studied

Sponsor

Centre Hospitalier Universitaire de Besancon

Who can join

60 and older, any sex, with Alzheimer's Disease or Progressive Primary Aphasia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the effect of 10 sessions of anodal transcranial Direct Current Stimulation (tDCS - 1 mA) applied to left Cortex DorsoLateral PreFrontal (CDLPF) of Alzheimer's or Primary Progressive Aphasia (PPA) patients compared to the application of a placebo tDCS (sham procedure) on cognitive functions, which are evaluated at short term (1 week post-treatment) and mild term (3 weeks post-treatment). After unblinding, patients who received placebo treatment could be received active tDCS.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Alzheimer's disease drug development pipeline: 2019.
    Cummings J, Lee G, Ritter A, Sabbagh M, et al · · 2019 · cited 485× · PMID 31334330 · DOI 10.1016/j.trci.2019.05.008
  2. Alzheimer's Disease: Models and Molecular Mechanisms Informing Disease and Treatments.
    Nystuen KL, McNamee SM, Akula M, Holton KM, et al · · 2024 · cited 18× · PMID 38247923 · DOI 10.3390/bioengineering11010045
  3. Non-pharmacological interventions for improving language and communication in people with primary progressive aphasia.
    Roheger M, Riemann S, Brauer A, McGowan E, et al · · 2024 · cited 13× · PMID 38808659 · DOI 10.1002/14651858.cd015067.pub2

Verify or expand the search:

Other trials of transcranial Direct Current Stimulation (tDCS)

Trials testing the same drug.

Other recruiting trials for Alzheimer's Disease

Currently open trials in the same condition.

Other Centre Hospitalier Universitaire de Besancon trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02873546.

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