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NCT02865421: AGA

Adipose Tissue Derived Stem Cell Based Hair Restoration Therapy for Androgenetic Alopecia

Completed Phase 2 Last updated 11 January 2018
What this trial tests

Phase 2 trial testing stem cells in Combination of SVF and PRP for Androgenetic Alopecia in 22 participants. Completed in 31 December 2017.

Timeline
10 June 2017
Primary endpoint
12 August 2017
31 December 2017

Quick facts

Lead sponsorKing Edward Medical University
PhasePhase 2
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment22
Start date10 June 2017
Primary completion12 August 2017
Estimated completion31 December 2017
Sites1 location across Pakistan

Drugs / interventions tested

Conditions studied

Sponsor

King Edward Medical University

Who can join

Adults 15 to 70, any sex, with Combination of SVF and PRP for Androgenetic Alopecia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Androgenetic alopecia (AGA) is a common form of hair loss in both men and women, characterized by progressive patterned loss of hair from the scalp. The current study has been designed for restoration of hair in AGA by using a combination of stromal vascular fraction (derived from the adipose tissue) and human platelet rich plasma.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging.
    Gaur M, Dobke M, Lunyak VV. · · 2017 · cited 105× · PMID 28117680 · DOI 10.3390/ijms18010208
  2. Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.
    Shimizu Y, Ntege EH, Sunami H, Inoue Y. · · 2022 · cited 77× · PMID 36382136 · DOI 10.1016/j.reth.2022.10.005
  3. Therapeutic Potential of Stem Cells in Follicle Regeneration.
    Owczarczyk-Saczonek A, Krajewska-Włodarczyk M, Kruszewska A, Banasiak Ł, et al · · 2018 · cited 46× · PMID 30154860 · DOI 10.1155/2018/1049641
  4. The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds).
    Owczarczyk-Saczonek A, Wociór A, Placek W, Maksymowicz W, et al · · 2017 · cited 22× · PMID 28904532 · DOI 10.1155/2017/4740709
  5. Advances in Stem Cell-Based Therapy for Hair Loss.
    Egger A, Tomic-Canic M, Tosti A. · · 2020 · cited 20× · PMID 32968692
  6. Stromal Vascular Fraction and its Role in the Management of Alopecia: A Review.
    Stefanis AJ, Groh T, Arenbergerova M, Arenberger P, et al · · 2019 · cited 12× · PMID 32038756

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