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NCT02858414: EURECA
Exploratory Study of Cellular Reservoirs in Blood From HIV Infected Patients
NA trial testing additional blood sample in HIV Infection in 41 participants. Completed in 4 October 2017.
4 October 2017
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Besancon |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 41 |
| Start date | 2 April 2015 |
| Primary completion | 4 October 2017 |
| Estimated completion | 4 October 2017 |
| Sites | 1 location across France |
Drugs / interventions tested
- additional blood sample — full drug profile →
Conditions studied
- HIV Infection — all drugs for HIV Infection →
Sponsor
Centre Hospitalier Universitaire de Besancon
Who can join
Adults 18 to 70, any sex, with HIV Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study evaluates the impact of highly active antiretroviral therapy on the size of the latent viral reservoirs in resting CD4+ T cells and monocytes in HIV positive patients. The activation state of the cells will be assessed, by measuring the activation of Akt, to determine its influence on the size of the viral reservoirs.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Counteracting Akt Activation by HIV Protease Inhibitors in Monocytes/Macrophages.
Pasquereau S, Kumar A, Abbas W, Herbein G. · · 2018 · cited 13× · PMID 29652795 · DOI 10.3390/v10040190
Verify or expand the search:
- PubMed search for NCT02858414
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Centre Hospitalier Universitaire de Besancon trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02858414 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Besancon
- Last refreshed: 6 December 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02858414.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing