NCT02853357 is a NA clinical trial of Manipulation in Low Back Pain, sponsored by University of Michigan.

Who is sponsoring NCT02853357?

NCT02853357 is sponsored by University of Michigan.

What drugs are being tested in NCT02853357?

Interventions in NCT02853357: Manipulation, Sham Manipulation, Core Strengthening Exercises.

What condition does NCT02853357 study?

NCT02853357 studies Low Back Pain.

Is NCT02853357 still recruiting?

NCT02853357 is currently completed. Last updated 31 May 2018.

Last reviewed 2018-05-31 · How we verify

NCT02853357

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Thoracic Spine Manipulation for Individuals With Low Back Pain

Completed NA Last updated 31 May 2018

What this trial tests

NA trial testing Manipulation in Low Back Pain in 101 participants. Completed in 30 May 2018.

Timeline

31 October 2016

Primary endpoint
30 April 2018

30 May 2018

Quick facts

Lead sponsor	University of Michigan
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	101
Start date	31 October 2016
Primary completion	30 April 2018
Estimated completion	30 May 2018

Drugs / interventions tested

Manipulation — full drug profile →
Sham Manipulation
Core Strengthening Exercises

Conditions studied

Low Back Pain — all drugs for Low Back Pain →

Sponsor

University of Michigan

Who can join

Adults 18 to 60, any sex, with Low Back Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine the short-term effects of thoracic spine thrust manipulation on participants with low back pain. Participants in this study will be randomized to receive either the lower thoracic spinal manipulation and a standard set of exercises, or a sham manipulation and the same standard set of exercises. It is hypothesized that thoracic manipulation when combined with core strengthening exercises will have positive short term improvements in pain and function for patients with LBP as compared to a sham manipulation combined with core strengthening exercises.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Short-term Effects of Thoracic Spine Thrust Manipulation, Exercise, and Education in Individuals With Low Back Pain: A Randomized Controlled Trial.
Fisher LR, Alvar BA, Maher SF, Cleland JA. · · 2020 · cited 10× · PMID 31810405 · DOI 10.2519/jospt.2020.8928

Verify or expand the search:

Other trials of Manipulation

Trials testing the same drug.

NCT06442540 — Effects of Intra Muscular Electrotherapy Combined With Manipulative Therapy in Patients With Sacral Torsion · NA · recruiting
NCT05474456 — Effects of Sustained Natural Apophyseal Glides Versus Cervical Manipulation on Pain and Disability in Wrestle · NA · completed
NCT02287337 — Validation of CPR for Manipulation for Neck Pain · NA · terminated

Other recruiting trials for Low Back Pain

Currently open trials in the same condition.

NCT07526012 — Comparative Effects Of Post Isometric Relaxation Versus Active Isolated Stretch In Patients With Piriformis Syndrome · NA · recruiting
NCT07535047 — Placebo-Induced Hypoalgesia During Transcutaneous Electrical Nerve Stimulation Application in Low Back Pain · NA · recruiting
NCT07463729 — Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome · NA · recruiting
NCT07250568 — Office Program Effects on Pain, Posture, Muscle Physiology, Stress, Ergonomics, and Quality of Life in LBP Workers · NA · recruiting
NCT07467070 — Effectiveness of Pilates on Postural Correction, Core Strength and Flexibility in Younger Individuals With Non-specific · NA · recruiting

Other University of Michigan trials

Trials by the same sponsor.

NCT07536919 — Integrating Care for Hypertension-Diabetes MULTImorbidity in Guatemala Through HEARTS Implementation · NA · not yet recruiting
NCT05509842 — Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD) · NA · not yet recruiting
NCT06311188 — Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness · NA · not yet recruiting
NCT07471646 — Effects of Ramadan Fasting With Exercise on Cardiometabolic Health · NA · not yet recruiting
NCT06671925 — A Community Health Worker-Led Program for Chronic Pain and Loneliness in Older Adults · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02853357 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Michigan
Last refreshed: 31 May 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02853357.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing