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NCT02849405

Evaluation of the Capacity of a Camera to Identify Signs of Arteriosclerosis in Retinal Arterioles

Completed NA Last updated 28 March 2024
What this trial tests

NA trial testing MHRC: Metabolic Hyperspectral Retinal Camera in Arteriosclerosis in 60 participants. Completed in 16 September 2021.

Timeline
21 December 2016
Primary endpoint
16 September 2021
16 September 2021

Quick facts

Lead sponsorJean-Claude Tardif
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposediagnostic
Enrollment60
Start date21 December 2016
Primary completion16 September 2021
Estimated completion16 September 2021
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

Jean-Claude Tardif

Who can join

18 and older, any sex, with Arteriosclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Arteriosclerosis is a degenerative and dysmetabolic disease of the arterial walls. It is known to be the principal cause of coronary artery disease (CAD). Arteriosclerosis has an impact on the entire vascularization including the microvascularization. The retina is a nervous tissue that is supported by microvascularization. Therefore, systemic diseases that affect the nervous or the cardiovascular system are susceptible to have manifestations in the retina. Retinal signs associated to the risks to develop CAD (qualitative appreciation; diameter and appearance of arterioles) have been suggested. A quantitative approach would strengthen the interpretation of these evaluations. The Metabolic Hyperspectral Retinal Camera (MHRC) - the experimental instrument - has the capacity to identify and quantify a variety of biomolecules specific to the retina and the optic nerve. The purpose of this pilot study is to determine if the MHRC has the capacity to detect a specific hyperspectral signature in the retinal arterioles of subjects suffering from arteriosclerosis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Data sources for this page

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