NCT02847793: ABMET

Attentional Bias Modification Through Eye-tracker Methodology (ABMET)

Completed NA Last updated 10 October 2018

What this trial tests

NA trial testing Gaze training in Cognitive Deficits in 32 participants. Completed in 28 July 2017.

Timeline

1 April 2016

Primary endpoint
1 April 2017

28 July 2017

Quick facts

Lead sponsor	Universidad Complutense de Madrid
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	basic science
Enrollment	32
Start date	1 April 2016
Primary completion	1 April 2017
Estimated completion	28 July 2017
Sites	1 location across Spain

Drugs / interventions tested

• Gaze training
• Placebo intervention

Conditions studied

• Cognitive Deficits — all drugs for Cognitive Deficits →
• Depression — all drugs for Depression →
• Alteration of Cognitive Function — all drugs for Alteration of Cognitive Function →

Sponsor

Universidad Complutense de Madrid — full company profile →

Who can join

18 and older, any sex, with Cognitive Deficits or Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cognitive biases are a hallmark of depression but there is scarce research on whether these biases can be directly modified by using specific cognitive training techniques.

The aim of this study will be targeting and modifying specifically relevant attention biases in participants with subclinical depression using eye-tracking methodologies. This innovative approach has been proposed as a promising future line of intervention in Attention Bias Modification procedures (Koster \& Hoorelbeke, 2015).

Recent findings suggest that depression is characterized by a double attentional bias (Duque \& Vazquez, 2015), More specifically, depressed individuals have difficulties both to disengage from negative materials (e.g., sad faces) and to engage with positive materials (e.g., happy faces). Thus, training procedures to change attentional biases should target these two separate components.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Attentional bias modification in depression through gaze contingencies and regulatory control using a new eye-tracking intervention paradigm: study protocol for a placebo-controlled trial.
   Vazquez C, Blanco I, Sanchez A, McNally RJ. · · 2016 · cited 20× · PMID 27931196 · DOI 10.1186/s12888-016-1150-9