NCT02832492 is a clinical trial of pupil near response in Vegetative State, sponsored by Wentao Zeng.

Who is sponsoring NCT02832492?

NCT02832492 is sponsored by Wentao Zeng.

What drugs are being tested in NCT02832492?

Interventions in NCT02832492: pupil near response.

What condition does NCT02832492 study?

NCT02832492 studies Vegetative State.

Is NCT02832492 still recruiting?

NCT02832492 is currently completed. Last updated 4 August 2022.

Last reviewed 2022-08-04 · How we verify

NCT02832492

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Prognostic Value of Pupil Near Response in UWS Patients

Completed Last updated 4 August 2022

What this trial tests

trial testing pupil near response in Vegetative State in 20 participants. Completed in 10 February 2016.

Timeline

29 October 2015

Primary endpoint
10 February 2016

10 February 2016

Quick facts

Lead sponsor	Wentao Zeng
Status	Completed
Study type	OBSERVATIONAL
Enrollment	20
Start date	29 October 2015
Primary completion	10 February 2016
Estimated completion	10 February 2016

Drugs / interventions tested

pupil near response

Conditions studied

Vegetative State — all drugs for Vegetative State →

Sponsor

Wentao Zeng

Who can join

Adults 6 to 85, any sex, with Vegetative State. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Previous studies suggest that the stimulus of pupil near response (PNR) may be a conscious perception of a blurred image. Moreover, PNR is a reflex that can be objectively observed and with no motor output, suggesting it might be a more convenient index for consciousness evaluation and consciousness recovery in patients with disorders of consciousness (DOC). We thus hypothesized that PNR+ patients (patients show PNR during the assessment) would have better prognosis than PNR- patients (patients fail to show PNR during the assessment).Based on this hypotheis, researchers will assess pupil near response in patients with unresponsive wakefulness syndrome (UWS) and compare the prognosis difference between PNR+ patients and PNR- patients to assess its prognosis value.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Vegetative State

Currently open trials in the same condition.

NCT04065386 — Transcutaneous Auricular Vagal Nerve Stimulation for Post-coma Patients With Disorders of Consciousness · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02832492 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Wentao Zeng
Last refreshed: 4 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02832492.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing