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NCT02826837
LEAC-102 for Advanced Colorectal Cancer
Phase 1, PHASE2 trial testing LEAC-102 500mg capsule and FOLFOX + Bevacizumab/Cetuximab in Advanced Colorectal Cancer in 30 participants. Status unknown.
1 February 2024
Quick facts
| Lead sponsor | Taiwan Leader Biotech Corp. |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 September 2022 |
| Primary completion | 1 February 2024 |
| Estimated completion | 1 February 2024 |
Drugs / interventions tested
- LEAC-102 500mg capsule and FOLFOX + Bevacizumab/Cetuximab — full drug profile →
Conditions studied
- Advanced Colorectal Cancer — all drugs for Advanced Colorectal Cancer →
Sponsor
Taiwan Leader Biotech Corp. — full company profile →
Who can join
Adults 20 to 75, any sex, with Advanced Colorectal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A Phase I/IIa Dose-Escalation Study Evaluating the Safety, Tolerability and Efficacy of LEAC-102 in Combination with FOLFOX + Bevacizumab/Cetuximab in Subjects with Advanced Colorectal Cancer
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Can immunotherapy reinforce chemotherapy efficacy? a new perspective on colorectal cancer treatment.
He X, Lan H, Jin K, Liu F. · · 2023 · cited 12× · PMID 37790928 · DOI 10.3389/fimmu.2023.1237764
Verify or expand the search:
- PubMed search for NCT02826837
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02826837 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Taiwan Leader Biotech Corp.
- Last refreshed: 6 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02826837.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing