Who is sponsoring PRP-E?

PRP-E is sponsored by University of California, San Francisco.

What condition does PRP-E study?

PRP-E studies Infertility, Asherman's Syndrome.

What drugs are being tested in PRP-E?

Interventions: Intrauterine infusion of platelet rich plasma.

Last reviewed 2021-01-21 · How we verify

Platelet-rich Plasma (PRP) for Endometrial Regeneration and Repair: a Prospective Randomised Pilot Study (PRP-E)

NCT02825849 Phase 2 TERMINATED Results posted

Patients with intrauterine adhesions (Asherman's Syndrome) and persistent thin endometrial lining in in vitro fertilization (IVF) treatment programs, particularly those resistant to standard therapies, present a significant clinical challenge. The aim of this trial is to assess if intrauterine administration of platelet rich plasma (PRP) improves endometrial lining thickness in patients with thin lining or Asherman's Syndrome.

Details

Lead sponsor	University of California, San Francisco
Phase	Phase 2
Status	TERMINATED
Enrolment	27
Start date	2016-11
Completion	2019-08

Conditions

Infertility
Asherman's Syndrome

Interventions

Intrauterine infusion of platelet rich plasma

Primary outcomes

Endometrial Thickness — 3-30 days after treatment
Endometrial thickness will be measured using transvaginal ultrasound per standard protocol

Countries

United States