Who is sponsoring NCT02824770?

NCT02824770 is sponsored by Eskisehir Osmangazi University.

What drugs are being tested in NCT02824770?

Interventions in NCT02824770: Dimming of lights and decreasing noise level, Bupivacaine (Bustesin®) via Pain Buster ® system, Tramadol HCl (Tramosel®) via PCA system (Gemstar®), Major abdominal surgery.

What condition does NCT02824770 study?

NCT02824770 studies Sleep Deprivation.

Is NCT02824770 still recruiting?

NCT02824770 is currently status unknown. Last updated 7 June 2017.

Last reviewed 2017-06-07 · How we verify

NCT02824770

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Sleep Quality on Melatonin Levels and Inflammatory Response After Major Abdominal Surgery

Status unknown NA Last updated 7 June 2017

What this trial tests

NA trial testing Dimming of lights and decreasing noise level in Sleep Deprivation in 40 participants. Status unknown.

Timeline

1 January 2017

Primary endpoint
30 June 2017

1 July 2017

Quick facts

Lead sponsor	Eskisehir Osmangazi University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	40
Start date	1 January 2017
Primary completion	30 June 2017
Estimated completion	1 July 2017
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Dimming of lights and decreasing noise level
Bupivacaine (Bustesin®) via Pain Buster ® system — full drug profile →
Tramadol HCl (Tramosel®) via PCA system (Gemstar®) — full drug profile →
Major abdominal surgery

Conditions studied

Sleep Deprivation — all drugs for Sleep Deprivation →

Sponsor

Eskisehir Osmangazi University

Who can join

Adults 18 to 65, any sex, with Sleep Deprivation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Endogenous melatonin is produced by the pineal gland at night under normal conditions and regulates the sleep-wake cycle. Artificial light administered at night suppresses melatonin production and sleep disturbances are accompanied by abnormal melatonin secretion such as phase delay. Therefore, dramatic disturbances of endogenous rhythms in intensive care unit patients have remarkable effects on melatonin production. In addition to its physiological roles in regulating sleep patterns, melatonin has been demonstrated to provide antiinflammatory effects in experimental models. Although some previous studies have investigated the circadian pattern of melatonin in intensive care unit patients, the investigators think that the present study is the first one that will assess the effects of controlling noise and light on melatonin and inflammatory response after major abdominal surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of Sleep Quality on Melatonin Levels and Inflammatory Response after Major Abdominal Surgery in an Intensive Care Unit.
Yaşar NF, Badak B, Canik A, Baş SŞ, et al · · 2017 · cited 9× · PMID 28895895 · DOI 10.3390/molecules22091537

Verify or expand the search:

Other recruiting trials for Sleep Deprivation

Currently open trials in the same condition.

NCT07438912 — Mind After Midnight · NA · recruiting
NCT07329283 — Nighttime Synchrony of Your Nutrition and Circadian Health · NA · recruiting
NCT07294781 — Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness · NA · recruiting
NCT07085754 — Effects of Acute Sleep Deprivation on Individuals With Different APOE Genotypes · NA · recruiting
NCT06492109 — The Peripheral Blood Multi-Omics Study on Sleep Loss · NA · recruiting

Other Eskisehir Osmangazi University trials

Trials by the same sponsor.

NCT07343505 — Environmental Enrichment Intervention and Brain Development in Preterm Infants · NA · not yet recruiting
NCT07346963 — RSV-Positive Children <5 Years Presenting to Pediatric Emergency Departments in Türkiye: TRUST-RSV · not yet recruiting
NCT07342101 — Evaluating the LGG of on Acute Infectious Diarrhea in Children · NA · not yet recruiting
NCT07307924 — The Effect of Motivational Interviewing on Knowledge, Self-Efficacy, and Treatment Adherence in Patients With Primary Hy · NA · enrolling by invitation
NCT07131267 — Evaluating Sexual Functioning in Trans Men During the Gender Affirmation Process: A Mixed Methods Study · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02824770 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Eskisehir Osmangazi University
Last refreshed: 7 June 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02824770.

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