Effect of Intravenous Hyoscine Butylbromide Injection on the Course and Duration of First Stage of Labour in Primigavidae

NCT02824679 Phase 4 COMPLETED

A case control study conducted on 120 women coming to Cairo University Maternity Hospital .Patients who meet the inclusion criteria were asked to participate in the study and a verbal consent was obtained from each patient. Patients will be divided into three equal groups (A, B, C). A single dose of the drug (placebo or HBB 20mg or HBB 40 mg) will be injected intravenously slowly to groups A, B, C respectively. Labouring mothers will be monitored in bed. Vaginal examination will be conducted every two hours. The duration of the first stage was calculated from the time of cervical dilatation of three to four centimeters in active labour until a fully dilated cervix will be observed

Details

Lead sponsor	Ahmed M Maged, MD
Phase	Phase 4
Status	COMPLETED
Enrolment	200
Start date	2015-07
Completion	2017-03

Conditions

• Vaginal Delivery

Interventions

• hyoscine butylbromide
• saline

Primary outcomes

• first stage duration — 12 hours after drug intake
  time till cervix become fully dilated