NCT02823431 is a NA clinical trial of lidocaine gel in Urethral Analgesia, sponsored by Duke University.

Who is sponsoring NCT02823431?

NCT02823431 is sponsored by Duke University.

What drugs are being tested in NCT02823431?

Interventions in NCT02823431: lidocaine gel, Plain aqueous gel.

What condition does NCT02823431 study?

NCT02823431 studies Urethral Analgesia.

Is NCT02823431 still recruiting?

NCT02823431 is currently completed. Last updated 23 October 2017.

Are results published for NCT02823431?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2017-10-23 · How we verify

NCT02823431

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Contribution of Urethral Sensory Feedback in Voiding Efficiency

Completed NA Results posted Last updated 23 October 2017

What this trial tests

NA trial testing lidocaine gel in Urethral Analgesia in 23 participants. Completed in 1 December 2016.

Timeline

1 July 2016

Primary endpoint
1 December 2016

1 December 2016

Quick facts

Lead sponsor	Duke University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	basic science
Enrollment	23
Start date	1 July 2016
Primary completion	1 December 2016
Estimated completion	1 December 2016
Sites	1 location across United States

Drugs / interventions tested

lidocaine gel
Plain aqueous gel — full drug profile →

Conditions studied

Urethral Analgesia — all drugs for Urethral Analgesia →

Sponsor

Duke University

Who can join

Adults 18 to 60, female only, with Urethral Analgesia. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Voiding Efficiency
Time frame: duration of urodynamic study, 2 hours
voided volume/{voided volume + residual volume} during micturition study during urodynamic studies

Sponsor's own description

The purpose of this study is to evaluate how urethral analgesia impacts voiding efficiency in healthy women. The investigator hypothesizes that anesthetizing the urethral with lidocaine gel will decrease voiding efficiency as measured by standard bladder testing (urodynamic testing).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Randomized Controlled Trial to Assess the Impact of Intraurethral Lidocaine on Urodynamic Voiding Parameters.
Kisby CK, Gonzalez EJ, Visco AG, Amundsen CL, et al · · 2019 · cited 7× · PMID 29300256 · DOI 10.1097/spv.0000000000000544

Verify or expand the search:

Other trials of lidocaine gel

Trials testing the same drug.

NCT06493136 — Etude de l'ANesthésie Par Gel de Lidocaïne Pour Les Injections IntrA vitréennes · completed
NCT03637582 — Contribution of Urethral Sensory Feedback in Voiding Efficiency · NA · completed
NCT03166111 — Lidocaine In-situ Gel Prior to Intrauterine Device Insertion in Women With no Previous Vaginal Delivery · Phase 3 · completed
NCT03347721 — Does Lidocaine Gel Decrease Pain Perception in Women Undergoing Diagnostic Flexible Cystoscopy · Phase 4 · unknown
NCT03143452 — Comparison Between 2% Lidocaine Gel and 5% Tetracaine Eye Drop as Topical Anesthesia in Phacoemulsification · NA · completed

Other Duke University trials

Trials by the same sponsor.

NCT07216456 — Vaginal Dilator Therapy After Pelvic Radiation · NA · not yet recruiting
NCT07519317 — Dosing and Deployment Trial: A Home-based Optokinetic Treatment · NA · not yet recruiting
NCT07275359 — Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations · Phase 1 · not yet recruiting
NCT07216963 — The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study · NA · not yet recruiting
NCT07459218 — IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02823431 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Duke University
Last refreshed: 23 October 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02823431.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing