Effects of Intensive Antihypertensive Therapies on the Risk of Stroke in Hypertensive Adults: A Prospective Randomized Open-Label Blinded-Endpoint Trial, a Feasibility Study

NCT02817503 Phase 4 UNKNOWN

The purpose of the current feasibility study is to test whether the blood pressure level of the study patients can be effectively and safely managed according to the intensive antihypertensive treatment protocol. Furthermore, the study will also examine the effect of intensive antihypertensive treatment on the intermediate cardiovascular diseases outcomes, including CIMT, carotid plaques, PWV ABI, and kidney function, etc.

Details

Lead sponsor	Second Affiliated Hospital of Nanchang University
Phase	Phase 4
Status	UNKNOWN
Enrolment	100
Start date	2015-12
Completion	2016-12

Conditions

• Hypertension
• Hyperhomocysteinemia

Interventions

• Standard BP control
• Moderate BP control
• Intensive BP control

Primary outcomes

• Achieved mean blood pressure levels in each of the treatment groups — 6 months BP titration treatment period

Countries

China