NCT02816086: IMMENSE

A New Interdisciplinary Collaboration Structure to Improve Medication Safety in the Elderly

Completed NA Last updated 30 September 2021

What this trial tests

NA trial testing Interdisciplinary collaboration structure in Health Services for the Aged in 516 participants. Completed in 20 December 2020.

Timeline

21 September 2016

Primary endpoint
20 December 2020

20 December 2020

Quick facts

Lead sponsor	University of Tromso
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	health services research
Enrollment	516
Start date	21 September 2016
Primary completion	20 December 2020
Estimated completion	20 December 2020
Sites	1 location across Norway

Drugs / interventions tested

• Interdisciplinary collaboration structure

Conditions studied

• Health Services for the Aged — all drugs for Health Services for the Aged →
• Medication Therapy Management — all drugs for Medication Therapy Management →

Sponsor

University of Tromso

Who can join

70 and older, any sex, with Health Services for the Aged or Medication Therapy Management. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Suboptimal use of medications among geriatric patients is well-known problem and leads to medication errors, re-hospitalizations and death. By using a randomized controlled trial (RCT) design the investigators aim to explore a new inter-professional working structure. The working structure is based on the scientifically and clinically acknowledged integrated medicines management (IMM) model. The overall aim of the study is to explore the effect of the new working structure on the composite endpoint re-hospitalization + visit to an emergency department during 12 months after hospital discharge.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

1. Interventions to improve the appropriate use of polypharmacy for older people.
   Rankin A, Cadogan CA, Patterson SM, Kerse N, et al · · 2018 · cited 265× · PMID 30175841 · DOI 10.1002/14651858.cd008165.pub4
2. Medication review in hospitalised patients to reduce morbidity and mortality.
   Bülow C, Clausen SS, Lundh A, Christensen M. · · 2023 · cited 37× · PMID 36688482 · DOI 10.1002/14651858.cd008986.pub4
3. Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial.
   Johansen JS, Havnes K, Halvorsen KH, Haustreis S, et al · · 2018 · cited 23× · PMID 29362276 · DOI 10.1136/bmjopen-2017-020106
4. Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (The IMMENSE study) - a randomized controlled trial.
   Johansen JS, Halvorsen KH, Svendsen K, Havnes K, et al · · 2022 · cited 10× · PMID 36289541 · DOI 10.1186/s12913-022-08648-1
5. A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults.
   Robinson EG, Gyllensten H, Johansen JS, Havnes K, et al · · 2023 · cited 2× · PMID 37991657 · DOI 10.1007/s40266-023-01077-7
6. Investigating the impact of a pharmacist intervention on inappropriate prescribing practices at hospital admission and discharge in older patients: a secondary outcome analysis from a randomized controlled trial.
   Garcia BH, Omma KK, Småbrekke L, Johansen JS, et al · · 2024 · cited 1× · PMID 39555108 · DOI 10.1177/20420986241299683
7. Health-related quality of life among older adults following acute hospitalization: longitudinal analysis of a randomized controlled trial.
   Robinson EG, Gyllensten H, Granas AG, Halvorsen KH, et al · · 2024 · cited 1× · PMID 38884880 · DOI 10.1007/s11136-024-03689-x