NCT02814825 is a clinical trial of ViviGen in Cervical Spondylosis, sponsored by DePuy Spine.

Who is sponsoring NCT02814825?

NCT02814825 is sponsored by DePuy Spine.

What drugs are being tested in NCT02814825?

Interventions in NCT02814825: ViviGen.

What condition does NCT02814825 study?

NCT02814825 studies Cervical Spondylosis, Degenerative Intervertebral Discs, Herniated Disc.

Is NCT02814825 still recruiting?

NCT02814825 is currently completed. Last updated 17 February 2026.

Last reviewed 2026-02-17 · How we verify

NCT02814825

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

An ACDF Multi-Center Study Using ViviGen Cellular Bone Matrix

Completed Last updated 17 February 2026

What this trial tests

trial testing ViviGen in Cervical Spondylosis in 100 participants. Completed in 15 April 2021.

Timeline

1 June 2016

Primary endpoint
22 February 2021

15 April 2021

Quick facts

Lead sponsor	DePuy Spine
Status	Completed
Study type	OBSERVATIONAL
Enrollment	100
Start date	1 June 2016
Primary completion	22 February 2021
Estimated completion	15 April 2021

Drugs / interventions tested

ViviGen

Conditions studied

Cervical Spondylosis — all drugs for Cervical Spondylosis →
Degenerative Intervertebral Discs — all drugs for Degenerative Intervertebral Discs →
Herniated Disc — all drugs for Herniated Disc →

Sponsor

DePuy Spine — full company profile →

Who can join

Adults 21 to 75, any sex, with Cervical Spondylosis or Degenerative Intervertebral Discs. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this post-market study is to collect data on ViviGen and how its use affects fusion rates in the cervical spine when used as additional grafting material to fill the cervical spacer. The patient population of interest is patients who have already elected to undergo a 2-3 level ACDF surgical procedure using ViviGen, per standard of care.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Allografts and Spinal Fusion.
Cohen JD, Kanim LE, Tronits AJ, Bae HW. · · 2021 · cited 14× · PMID 34376497 · DOI 10.14444/8056

Verify or expand the search:

Other trials of ViviGen

Trials testing the same drug.

NCT04138017 — ViviGen Cellular Bone Matrix for Hindfoot or Ankle Arthrodesis · completed

Other recruiting trials for Cervical Spondylosis

Currently open trials in the same condition.

NCT06093997 — Study on the Treatment of C/S of Qi Stagnation and Blood-stasis Type by Moving Cupping with Bloodletting · NA · recruiting
NCT04623593 — Cervical Arthroplasty Cost Effectiveness Study (CACES) · NA · recruiting
NCT03320759 — Enhancing Recovery in Non-Traumatic Spinal Cord Injury · NA · recruiting

Other DePuy Spine trials

Trials by the same sponsor.

NCT00432159 — Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study) · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02814825 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by DePuy Spine
Last refreshed: 17 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02814825.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing