Last reviewed · How we verify
Effectiveness of Intraoperative Exparel, a Bupivacaine Liposome Injectable Suspension, for Postoperative Pain Control in Total Knee Arthroplasty: A Prospective, Randomized, Double Blind, Controlled Study
Does the use of periarticular Exparel in total knee arthroplasty prove to more effectively manage post operative pain control than another local analgesic, Ropivacaine, when both are used as part of a multimodal pain management approach? The investigators hypothesize that Exparel, a bupivacaine liposomal injectable suspension, will improve total knee arthroplasty postoperative pain with significant improvement of early function outcomes.
Details
| Lead sponsor | DeClaire LaMacchia Orthopaedic Institute |
|---|---|
| Phase | Phase 4 |
| Status | UNKNOWN |
| Enrolment | 100 |
| Start date | 2014-05 |
| Completion | 2016-06 |
Conditions
- Osteoarthritis
- Total Knee Arthroplasty
- Pain Management
Interventions
- Pain Cocktail with Exparel
- Pain Cocktail with Ropivacaine
Primary outcomes
- Postoperative opioid consumption — immediately post-operatively through hospital stay
oral and intravenous narcotic consumption is recorded during hospital stay