NCT02807922 is a Phase 4 clinical trial of Zopiclone in Sleep, sponsored by St. Olavs Hospital.

Who is sponsoring NCT02807922?

NCT02807922 is sponsored by St. Olavs Hospital.

What drugs are being tested in NCT02807922?

Interventions in NCT02807922: Zopiclone, Placebo.

What condition does NCT02807922 study?

NCT02807922 studies Sleep, Insomnia.

Is NCT02807922 still recruiting?

NCT02807922 is currently completed. Last updated 16 July 2021.

Last reviewed 2021-07-16 · How we verify

NCT02807922

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pharmacological Treatment of Insomnia in Palliative Care

Completed Phase 4 Last updated 16 July 2021

What this trial tests

Phase 4 trial testing Zopiclone in Sleep in 43 participants. Completed in 13 July 2021.

Timeline

15 November 2016

Primary endpoint
13 July 2021

13 July 2021

Quick facts

Lead sponsor	St. Olavs Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	43
Start date	15 November 2016
Primary completion	13 July 2021
Estimated completion	13 July 2021
Sites	5 locations across Norway

Drugs / interventions tested

Zopiclone (ZOPICLONE) — full drug profile →
Placebo

Conditions studied

Sleep — all drugs for Sleep →
Insomnia — all drugs for Insomnia →

Sponsor

St. Olavs Hospital

Who can join

18 and older, any sex, with Sleep or Insomnia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Sleep disturbance is frequent in patients with advanced cancer and decreases the tolerability of other symptoms and impairs quality of life. A detailed description of sleep disturbance and its association with other symptoms, and intervention studies on sleep medications are scarce in patients with advanced cancer. A well-designed randomized controlled trial is needed to determine the short time effectiveness of zopiclone on sleep quality, one of the currently available therapies of insomnia, and further to contribute to the clinical management of insomnia in patients with advanced cancer.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer-a double-blind, randomized placebo-controlled clinical multicenter phase IV trial.
Jakobsen G, Sjue K, Paulsen Ø, Kaasa S, et al · · 2022 · cited 6× · PMID 36534165 · DOI 10.1007/s00520-022-07537-x
Zopiclone versus placebo for short-term treatment of insomnia in patients with advanced cancer: study protocol for a double-blind, randomized, placebo-controlled, clinical multicenter trial.
Jakobsen G, Engstrøm M, Paulsen Ø, Sjue K, et al · · 2018 · cited 3× · PMID 30591073 · DOI 10.1186/s13063-018-3088-3

Verify or expand the search:

Other trials of Zopiclone

Trials testing the same drug.

NCT06219902 — A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women · Phase 1 · completed
NCT05819710 — A Study to Investigate the Next-day Residual Effects of TS-142 in Healthy Elderly Subjects · Phase 1 · completed
NCT04696952 — A Study to Evaluate Next Day Effects of TS-142 on Driving Performance in Healthy Subjects · Phase 1 · completed
NCT04451187 — A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants · Phase 1 · completed
NCT03351439 — Efficacy of Multimodal Analgesia Following Hip Arthroscopy · NA · completed

Other recruiting trials for Sleep

Currently open trials in the same condition.

NCT07413185 — Relationship Between the Severity of Sleep Deprivation in the First 48 Hours Postpartum, Breastfeeding Motivation, and B · recruiting
NCT07401212 — GUTLINK4KIDS Intervention · NA · recruiting
NCT07497698 — Saffron Extract Supplementation and Sleep Quality in Middle-Aged Adults · NA · recruiting
NCT07213908 — Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth · NA · recruiting
NCT06670287 — The Use of Multiple Sensors to Track Sleep in Nightshift Workers · NA · recruiting

Other St. Olavs Hospital trials

Trials by the same sponsor.

NCT07331766 — Collaboratory Treatment Pathway for Chronic Pain Patients. · NA · enrolling by invitation
NCT07305025 — Pelvic Pain Electro-Acupuncture · NA · not yet recruiting
NCT07245264 — Adjuvant Tranexamic Acid (TXA) Versus Surgery Alone for Adult Patients With Chronic Subdural Hematoma (CSDH) · Phase 2, PHASE3 · recruiting
NCT07180433 — Piloting 18F-FAPI PET/MRI for Applications in Breast Cancer · NA · not yet recruiting
NCT06854861 — Premixed Glucagon/Insulin Solution for Faster Insulin Absorption in Type 1 Diabetes · Phase 1, PHASE2 · suspended

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02807922 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by St. Olavs Hospital
Last refreshed: 16 July 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02807922.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing