Metformin for Prevention of Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome: Randomized Controlled Trial (RCT ) (MGDPCOS)

NCT02802215 Phase 2/Phase 3 UNKNOWN

Randomized, placebo controlled clinical trial that evaluate the role of taking metformin therapy during pregnancy in women with polycystic ovarian syndrome(PCOS) in reducing the development of gestational diabetes(GDM) and improving pregnancy outcomes.

Details

Lead sponsor	Ain Shams University
Phase	Phase 2/Phase 3
Status	UNKNOWN
Enrolment	80
Start date	2016-01
Completion	2016-09

Conditions

• Polycystic Ovary Syndrome
• Diabetes, Gestational

Interventions

• metformin
• placebo (folic acid )

Primary outcomes

• Number of participants with gestational diabetes by measuring plasma glucose levels ( mg / dl ). — 24th -28th week gestation
  Diagnosis of GDM when these values are met or exceed fasting plasma glucose level (92 mg/dl).1hr level is (180 mg/dl) and 2hrs level is (153 mg/dl).

Countries

Egypt