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NCT02798107

Observational Study to Evaluate Safety of Idarucizumab in Pediatric Patients

Withdrawn Last updated 18 November 2021
What this trial tests

trial testing idarucizumab in Hemorrhage. Withdrawn.

Timeline
20 May 2019
Primary endpoint
23 May 2019
24 May 2019

Quick facts

Lead sponsorBoehringer Ingelheim
StatusWithdrawn
Study typeOBSERVATIONAL
Start date20 May 2019
Primary completion23 May 2019
Estimated completion24 May 2019

Drugs / interventions tested

Conditions studied

Sponsor

Boehringer Ingelheim — full company profile →

Who can join

Under 17, any sex, with Hemorrhage. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Idarucizumab is a humanized monoclonal antibody fragment (Fab) that binds to dabigatran with very high affinity. Idarucizumab potently and specifically binds to dabigatran and its metabolites and neutralises its anticoagulant effect. A clinical development program is ongoing to support marketing authorisation submissions for idarucizumab indicated in patients treated with dabigatran who require emergency surgery/urgent procedures or who have a life-threatening or uncontrolledbleeding when rapid reversal of the anticoagulant effects of dabigatran is required.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Evidence for Idarucizumab (Praxbind) in the Reversal Of the Direct Thrombin Inhibitor Dabigatran: Review Following the RE-VERSE AD Full Cohort Analysis.
    Hutcherson TC, Cieri-Hutcherson NE, Bhatt R. · · 2017 · cited 6× · PMID 29089725

Verify or expand the search:

Other trials of idarucizumab

Trials testing the same drug.

Other recruiting trials for Hemorrhage

Currently open trials in the same condition.

Other Boehringer Ingelheim trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02798107.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing