Comparison of Local and Intra Venous Dexamethasone on Post Operative Pain and Recovery After Caeseream Section

NCT02784340 Phase 4 COMPLETED

A Prospective, randomized study conducted on 120 pregnant women attending the labour wards in Kasr Al Ainy and Fayoum maternity hospitals from May 2014 to December 2015. All participants were scheduled for elective cesarean section under spinal anaesthesia and were randomly divided into 3 equal groups. Group 1(40 women) received 16 mg Dexamethasone IV drip. Group II (40 women) received 16 mg Dexamethasone subcutaneous injection around the caesarean section scar after skin closure and Group III received Placebo in the form of IV fluids 500 cc saline infusion. All cases were followed up for 48 hours for assessment of level of pain by using a 10-cm visual analog scale (VAS). Primary outcome parameters were VAS score and the need for additional analgesics. Other parameters were hemodynamic changes and occurrence of side effects or complications

Details

Lead sponsor	Cairo University
Phase	Phase 4
Status	COMPLETED
Enrolment	120
Start date	2014-05
Completion	2015-12

Conditions

• Postoperative Pain

Interventions

• Dexamethasone
• Dexamethasone
• Saline (IV fluids)
• Bupivicaine and Fentany
• 25G spinal needles

Primary outcomes

• VAS score visual acoustic score — 48 hours after CS
  Subjective description of the pain using questionaire