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NCT02783586

TAPB vs QLBII for Kidney Transplantation Procedure

Completed Phase 4 Last updated 22 May 2018
What this trial tests

Phase 4 trial testing Quadratus Lumborum Block type II in Postoperative Pain in 104 participants. Completed in 30 May 2017.

Timeline
8 April 2016
Primary endpoint
29 May 2017
30 May 2017

Quick facts

Lead sponsorMedical University of Warsaw
PhasePhase 4
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingtriple
Primary purposetreatment
Enrollment104
Start date8 April 2016
Primary completion29 May 2017
Estimated completion30 May 2017
Sites1 location across Poland

Drugs / interventions tested

Conditions studied

Sponsor

Medical University of Warsaw

Who can join

18 and older, any sex, with Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main advantage of Quadratus Lumborum Block (QLB) compared to Transversus Abdominalis Plane Block (TAPB) is the impact on visceral pain due to the spread of the local anaesthetic agent to the paravertebral space. It may produce extensive analgesia and better pain control. Previews studies shoved the effectiveness of TAPB in kidney transplantation procedure (KTX) by reducing opioids requirements during and after the operation. QLB was not evaluating in KTX procedure yet, but it reduced postoperative morphine requirement after cesarean section under spinal anaesthesia. The aim of this prospective, randomised controlled, multicenter, clinical study is to compare the perioperative analgesic efficacy of QLB and TAPB in patients who had KTX under balanced (general and regional) anaesthesia.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Transversus abdominis plane block versus quadratus lumborum block type 2 for analgesia in renal transplantation: A randomised trial.
    Kolacz M, Mieszkowski M, Janiak M, Zagorski K, et al · · 2020 · cited 18× · PMID 32175985 · DOI 10.1097/eja.0000000000001193

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Other recruiting trials for Postoperative Pain

Currently open trials in the same condition.

Other Medical University of Warsaw trials

Trials by the same sponsor.

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