Who is sponsoring NCT02769013?

NCT02769013 is sponsored by University Hospital Tuebingen.

What drugs are being tested in NCT02769013?

Interventions in NCT02769013: Pre-treatment follow up, S. haematobium treatment, Post treatment follow up, Olfactometer experiment.

What condition does NCT02769013 study?

NCT02769013 studies Malaria Transmission.

Is NCT02769013 still recruiting?

NCT02769013 is currently completed. Last updated 3 November 2020.

Last reviewed 2020-11-03 · How we verify

NCT02769013: TRANSMAL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity

Completed Last updated 3 November 2020

What this trial tests

trial testing Pre-treatment follow up in Malaria Transmission in 380 participants. Completed in 1 October 2020.

Timeline

1 April 2016

Primary endpoint
1 October 2019

1 October 2020

Quick facts

Lead sponsor	University Hospital Tuebingen
Status	Completed
Study type	OBSERVATIONAL
Enrollment	380
Start date	1 April 2016
Primary completion	1 October 2019
Estimated completion	1 October 2020
Sites	2 locations across Gabon, Ghana

Drugs / interventions tested

Pre-treatment follow up
S. haematobium treatment
Post treatment follow up
Olfactometer experiment

Conditions studied

Malaria Transmission — all drugs for Malaria Transmission →

Sponsor

University Hospital Tuebingen

Who can join

Adults 6 to 30, any sex, with Malaria Transmission. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Number of participants with Plasmodium falciparum gametocytes and/or asexual blood stages
Time frame: 15 months
Presence of Plasmodium falciparum gametocytes and/or asexual blood stages will be assessed by a quantitative real-time PCR assay in the blood obtained from participants. Unit of measurements for both parameters is numbers/µl.

Sponsor's own description

Assessing the effect of neglected tropical diseases on Plasmodium falciparum transmission in an area of co endemicity.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon.
Dejon-Agobé JC, Edoa JR, Honkpehedji YJ, Zinsou JF, et al · · 2019 · cited 28× · PMID 31823806 · DOI 10.1186/s13071-019-3836-6
Epidemiology of soil-transmitted helminth infections and the differential effect of treatment on the distribution of helminth species in rural areas of Gabon.
Edoa JR, Adégbitè BR, Honkpéhèdji YJ, Zinsou JF, et al · · 2024 · cited 10× · PMID 38163912 · DOI 10.1186/s41182-023-00567-z
Three monthly doses of 60 mg/kg praziquantel for Schistosoma haematobium infection is a safe and effective treatment regimen.
Darko SN, Hanson H, Twumasi-Ankrah S, Baffour-Awuah S, et al · · 2020 · cited 7× · PMID 32375658 · DOI 10.1186/s12879-020-05053-z
Soil-transmitted helminth infections: prevalence, incidence, post-treatment infection rate, and associated factors among children and young adults living in rural areas of Gabon
EDOA JR, Adégbitè BR, Honkpéhèdji YJ, Zinsou JF, et al · · 2023 · DOI 10.21203/rs.3.rs-3405627/v1

Verify or expand the search:

Other recruiting trials for Malaria Transmission

Currently open trials in the same condition.

NCT07389057 — Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug Administratio · NA · recruiting

Other University Hospital Tuebingen trials

Trials by the same sponsor.

NCT07378670 — DEfeating PEnile CAncer-2 · NA · recruiting
NCT07276503 — Verification of a New Predictive Delirium Score in Adults With Elective Cardiac Valve or Bypass Surgery With Perioperati · not yet recruiting
NCT07411365 — Dual-task Cognitive-motor Telerehabilitation in Persons With PD-MCI · NA · not yet recruiting
NCT06953791 — Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Pat · Phase 2 · recruiting
NCT07378891 — Artificial-Intelligence-based Early Detection of Diabetic Retinopathy (FUNDUS AI) · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02769013 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital Tuebingen
Last refreshed: 3 November 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02769013.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing