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The Use of Bevacizumab as a Modulator of Wound Healing Following Trabeculectomy Surgery: A Single Centre Randomised Controlled Phase III Pilot Study (RAFTS)
This is a phase III randomised controlled pilot study which aims to assess the effectiveness of the use of bevacizumab in patients who have undergone trabeculectomy surgery, which appear to be showing early signs of failure.
Details
| Lead sponsor | Moorfields Eye Hospital NHS Foundation Trust |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 6 |
| Start date | 2016-05 |
| Completion | 2019-05 |
Conditions
- Glaucoma
Interventions
- bevacizumab
- 5-fluorouracil
- Dexamethasone
Primary outcomes
- Time taken to recruit 30 subjects (from start of study) — study start date to18 months
- Proportion of patients who are eligible who agree to be randomized — study start date to 18 months
- Proportion of patients who are lost to follow up or who withdraw from the study — Baseline to 36 months
Countries
United Kingdom