NCT02766725 (ss) is a Phase 2/Phase 3 clinical trial of preparation F12 sildenafil in situ gel in Infertility, sponsored by Assiut University.

Who is sponsoring NCT02766725?

NCT02766725 is sponsored by Assiut University.

What drugs are being tested in NCT02766725?

Interventions in NCT02766725: preparation F12 sildenafil in situ gel, preparation F2 sildenafil in situ gel, placebo gel.

What condition does NCT02766725 study?

NCT02766725 studies Infertility.

Is NCT02766725 still recruiting?

NCT02766725 is currently completed. Last updated 14 August 2020.

Last reviewed 2020-08-14 · How we verify

NCT02766725: ss

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Development and Clinical Evaluation of Thermosensitive Gels for the Vaginal Delivery of Sildenafil Citrate on the Endometrium of Women Use Clomiphene Citrate for Induction of Ovulation

Completed Phase 2/Phase 3 Last updated 14 August 2020

What this trial tests

Phase 2/Phase 3 trial testing preparation F12 sildenafil in situ gel in Infertility in 90 participants. Completed in 1 December 2015.

Timeline

1 January 2015

Primary endpoint
1 November 2015

1 December 2015

Quick facts

Lead sponsor	Assiut University
Phase	Phase 2/Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	90
Start date	1 January 2015
Primary completion	1 November 2015
Estimated completion	1 December 2015

Drugs / interventions tested

preparation F12 sildenafil in situ gel — full drug profile →
preparation F2 sildenafil in situ gel — full drug profile →
placebo gel

Conditions studied

Infertility — all drugs for Infertility →

Sponsor

Assiut University

Who can join

Adults 20 to 40, female only, with Infertility. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

The change of Doppler resistance index after the treatment
Time frame: 10 days

Sponsor's own description

The aim of this study was to develop and characterize in situ thermosensitive gels for the vaginal administration of sildenafil as a potential treatment of the endometrial thinning that occurs as a result of the use of clomiphene citrate in induction of ovulation in women with World Health Organization type II EU gonadotrophic anovulation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Thermosensitive bioadhesive gels for the vaginal delivery of sildenafil citrate: in vitro characterization and clinical evaluation in women using clomiphene citrate for induction of ovulation.
Soliman GM, Fetih G, Abbas AM. · · 2017 · cited 35× · PMID 27783532 · DOI 10.1080/03639045.2016.1254239

Verify or expand the search:

Other recruiting trials for Infertility

Currently open trials in the same condition.

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NCT07153367 — Using a Fixed Dosage of Follitropin Delta for Ovarian Stimulation for Intrauterine Insemination: Rekovelle for Intrauter · Phase 2 · recruiting

Other Assiut University trials

Trials by the same sponsor.

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NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02766725 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Assiut University
Last refreshed: 14 August 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02766725.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing