NCT02765516 (GenePredict-PS) is a NA clinical trial of Plant sterols in Hypercholesterolemia, sponsored by University of Manitoba.

Who is sponsoring NCT02765516?

NCT02765516 is sponsored by University of Manitoba.

What drugs are being tested in NCT02765516?

Interventions in NCT02765516: Plant sterols, Placebo.

What condition does NCT02765516 study?

NCT02765516 studies Hypercholesterolemia, Cardiovascular Disease.

Is NCT02765516 still recruiting?

NCT02765516 is currently terminated. Last updated 1 June 2020.

Last reviewed 2020-06-01 · How we verify

NCT02765516: GenePredict-PS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Genetic Basis for Prediction of Non-responders to Dietary Plant Sterol Intervention

Terminated NA Last updated 1 June 2020

What this trial tests

NA trial testing Plant sterols in Hypercholesterolemia in 43 participants. Terminated before completion.

Timeline

5 July 2017

Primary endpoint
31 December 2019

31 December 2019

Quick facts

Lead sponsor	University of Manitoba
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	prevention
Enrollment	43
Start date	5 July 2017
Primary completion	31 December 2019
Estimated completion	31 December 2019
Sites	1 location across Canada

Drugs / interventions tested

Plant sterols
Placebo

Conditions studied

Hypercholesterolemia — all drugs for Hypercholesterolemia →
Cardiovascular Disease — all drugs for Cardiovascular Disease →

Sponsor

University of Manitoba

Who can join

Adults 18 to 70, any sex, with Hypercholesterolemia or Cardiovascular Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objective of this study is to utilize information on associations between genetic predisposition pertaining to multiple single nucleotide polymorphisms (SNPs) and the degree of responsiveness of low-density lipoprotein cholesterol (LDL-C) lowering to plant sterols (PS). The predictive potential of SNPs associated with PS responsiveness will be evaluated using a randomized human intervention trial examining responsiveness of lowering blood LDL-C levels to PS intervention.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Genetic basis for prediction of non-responders to dietary plant sterol intervention (GenePredict-PS): a study protocol for a double-blind, placebo-controlled, randomized two-period crossover study.
Shamloo M, Granger MJ, Trautwein EA, House JD, et al · · 2020 · cited 2× · PMID 32487131 · DOI 10.1186/s13063-020-04364-5
Genetic basis for prediction of non-responders to dietary plant sterol intervention (GenePredict-PS): a study protocol for a double-blind, placebo-controlled, randomized two-period crossover study
Shamloo M, Granger MJ, Trautwein EA, House JD, et al · · 2020 · DOI 10.21203/rs.2.469/v2

Verify or expand the search:

Other recruiting trials for Hypercholesterolemia

Currently open trials in the same condition.

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NCT06568601 — Pharmacogenomic Informed Statin Prescribing · NA · recruiting
NCT06423365 — A Tool to Help Patients With Muscle Symptoms After Taking a Statin Medication. · NA · active not recruiting

Other University of Manitoba trials

Trials by the same sponsor.

NCT07528417 — Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX) · Phase 2 · not yet recruiting
NCT07366515 — Feasibility of a Multimodal Virtual Reality Intervention to Reduce Preoperative Anxiety in Cancer Surgery Patients · NA · not yet recruiting
NCT07354386 — Effects of Dried Whole Fruits on Metabolism in Diabetes · NA · enrolling by invitation
NCT07361315 — Development and Online Evaluation of an Online Course for Parasomnias · NA · recruiting
NCT07023744 — CANnabinoids for Drug Resistant Epilepsy (DRE) in Adults and Children · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02765516 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Manitoba
Last refreshed: 1 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02765516.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing