NCT02761746 (MESA) is a NA clinical trial of MESA in Medication Adherence, sponsored by Wayne State University.

Who is sponsoring NCT02761746?

NCT02761746 is sponsored by Wayne State University.

What drugs are being tested in NCT02761746?

Interventions in NCT02761746: MESA.

What condition does NCT02761746 study?

NCT02761746 studies Medication Adherence.

Is NCT02761746 still recruiting?

NCT02761746 is currently completed. Last updated 19 August 2022.

Last reviewed 2022-08-19 · How we verify

NCT02761746: MESA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Motivational Enhancement System for Adherence (MESA) for Youth Starting ART

Completed NA Last updated 19 August 2022

What this trial tests

NA trial testing MESA in Medication Adherence in 155 participants. Completed in 30 April 2021.

Timeline

22 February 2016

Primary endpoint
30 April 2021

30 April 2021

Quick facts

Lead sponsor	Wayne State University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	155
Start date	22 February 2016
Primary completion	30 April 2021
Estimated completion	30 April 2021
Sites	7 locations across United States

Drugs / interventions tested

MESA — full drug profile →

Conditions studied

Medication Adherence — all drugs for Medication Adherence →

Sponsor

Wayne State University

Who can join

Adults 16 to 24, any sex, with Medication Adherence. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is a multi-site (Detroit, MI; Los Angeles, CA; Philadelphia, PA, Washington, DC; Aurora, CO; Miami, FL; and Baltimore, MD), two-group randomized controlled trial testing a two-session intervention designed to increase motivation for adherence to antiretroviral treatment (ART) among youth living with HIV (YLH) newly recommended to begin medications. Participants are randomized to receive the intervention, Motivational Enhancement System for Adherence (MESA), or the control condition, System for Health (SH: healthy eating and physical activity information). Both groups receive the standard of care regarding the initiation of ART. ART adherence (visual analog scale and hair sample assay) and health outcomes (viral load results, and CD4 counts) are assessed. Additionally, potential mediators (HIV knowledge, motivation for adherence, and self-efficacy for adherence) and predictors of intervention response (substance abuse, mental health symptoms, executive functioning, and stressful life events) are assessed.

Publications & conference data

4 peer-reviewed publications reference this trial (live from Europe PMC):

Accuracy of measures for antiretroviral adherence in people living with HIV.
Smith R, Villanueva G, Probyn K, Sguassero Y, et al · · 2022 · cited 34× · PMID 35871531 · DOI 10.1002/14651858.cd013080.pub2
Antiretroviral adherence for adolescents growing up with HIV: understanding real life, drug delivery and forgiveness.
Foster C, Ayers S, Fidler S. · · 2020 · cited 30× · PMID 32523693 · DOI 10.1177/2049936120920177
Motivational Enhancement System for Adherence for Adolescents and Young Adults Newly Recommended to Start Antiretroviral Therapy.
Outlaw AY, Templin T, MacDonell K, Jones M, et al · · 2025 · PMID 39288943 · DOI 10.1097/qai.0000000000003530
Factors Impacting the Treatment Readiness of Youth Starting Antiretroviral Treatment in the United States.
Hall AL, Naar S, Outlaw AY, Templin T, et al · · 2024 · PMID 38742985 · DOI 10.1089/apc.2024.0072

Verify or expand the search:

Other recruiting trials for Medication Adherence

Currently open trials in the same condition.

NCT07420634 — Multilevel Ecological and COM-B Determinants of Medication Adherence in Adults With Diabetes · recruiting
NCT06876233 — Mobile Cued Adherence Therapy (mCAT) for Blood Pressure Medication · NA · recruiting
NCT05624931 — Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa · NA · recruiting
NCT06949774 — INcentives and ReMINDers to Improve Long-term Medication Adherence (INMIND) · NA · recruiting
NCT06569290 — Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Behavioral Sci · NA · active not recruiting

Other Wayne State University trials

Trials by the same sponsor.

NCT07219394 — Peer-Delivered Behavioral Activation in a CCBHC · NA · recruiting
NCT07123467 — Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder · Phase 3 · recruiting
NCT07222306 — Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study · enrolling by invitation
NCT05684978 — Efficacy and Safety of Perampanel in the Treatment of Refractory Status Epilepticus · Phase 4 · terminated
NCT06381180 — Warrior CARE: Cannabis Behavioral Health · Phase 1, PHASE2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02761746 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Wayne State University
Last refreshed: 19 August 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02761746.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing