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Transfusion of Biotinylated Red Blood Cells (b-RBCs)
The purpose of this research is to study how red blood cells (RBCs) survive in a person's circulation, and how that survival may be different in red blood cells that are donated and stored prior to being transfused. Investigators will study this by collecting blood samples from participants, "labeling" RBCs with a naturally occurring vitamin, biotin. The RBCs will then be re-infused back into the participant and blood samples will be taken weekly for 10 weeks to assess the number of labeled cells in the samples.
Details
| Lead sponsor | Emory University |
|---|---|
| Phase | PHASE1 |
| Status | COMPLETED |
| Enrolment | 5 |
| Start date | Wed Jan 11 2017 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Nov 13 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Anemia
Interventions
- Biotin-Labeled Red Blood Cells (RBCs)
Countries
United States