NCT02756585

Computed Tomography Perfusion in Patients With Severe Head Injury

Completed NA Last updated 21 August 2024

What this trial tests

NA trial testing ct perfusion in Brain Injuries in 21 participants. Completed in 1 October 2019.

Timeline

30 May 2016

Primary endpoint
1 October 2019

1 October 2019

Quick facts

Lead sponsor	Nova Scotia Health Authority
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	21
Start date	30 May 2016
Primary completion	1 October 2019
Estimated completion	1 October 2019
Sites	1 location across Canada

Drugs / interventions tested

• ct perfusion

Conditions studied

• Brain Injuries — all drugs for Brain Injuries →

Sponsor

Nova Scotia Health Authority — full company profile →

Who can join

18 and older, any sex, with Brain Injuries. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Traumatic brain injury (TBI) is a leading cause of post-injury hospitalization, disability, and death worldwide. In Nova Scotia, approximately 50% of major trauma reported is head trauma. TBI is predicted to be the most common and expensive neurological condition in Canada through the year 2031.

Families and medical teams must often decide on the appropriate level of care for patients with severe TBI and frequently need to consider withdrawal of life support measures. These decisions have implications for patients with severe TBI, costs to the health care system, and rates of organ donation.

A reliable method for neurological evaluation at the time of the patient's arrival to the hospital is important, because it is possible that many patients with severe TBI already have permanent brain damage. Assessing this brain damage with clinical tests is difficult because of the nature of patients' injuries and the sedative medication they receive at the time of their hospital admission. Current standard imaging technique for these patients is severely limited in the assessment of the extent and severity of the brain damage.

Advanced diagnostic imaging, called Computed Tomography Perfusion (CTP), can help detect permanent brain damage. However, CTP of the head is not currently done for patients with severe TBI when they arrive at the hospital. The investigators want to test whether CTP of the head can detect permanent brain damage among patients with severe TBI.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.