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NCT02755714
Atrovent in Exercise Induced Laryngeal Obstruction (EILO)
Phase 1, PHASE2 trial testing Ipratropium bromide spray in Exercise Induced Laryngeal Obstruction (EILO) in 20 participants. Completed in 31 October 2020.
31 October 2020
Quick facts
| Lead sponsor | Haukeland University Hospital |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 22 June 2016 |
| Primary completion | 31 October 2020 |
| Estimated completion | 31 October 2020 |
| Sites | 1 location across Norway |
Drugs / interventions tested
- Ipratropium bromide spray — full drug profile →
Conditions studied
- Exercise Induced Laryngeal Obstruction (EILO) — all drugs for Exercise Induced Laryngeal Obstruction (EILO) →
Sponsor
Haukeland University Hospital
Who can join
Adults 12 to 25, any sex, with Exercise Induced Laryngeal Obstruction (EILO). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Exercise Induced Laryngeal Obstruction (EILO) is a condition not uncommon in otherwise healthy young people. EILO is caused by posteromedial collapse of supraglottic structures or medialization of the vocal folds, or both, during high intensity exercise. There are currently no treatments available that is properly evidence based. However, case reports suggest a possible effect from the "asthma drug" Ipratropium Bromide (Atrovent®). The current project is an open label pilot study, aiming to test if Atrovent can influence the occurence of EILO, either postponing the onset during exercise or fully prevent the condition to occur.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT02755714
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Exercise Induced Laryngeal Obstruction (EILO)
Currently open trials in the same condition.
- NCT04620343 — HelpILO - RCT on EILO Treatment · NA · recruiting
Other Haukeland University Hospital trials
Trials by the same sponsor.
- NCT07450105 — Intensive Dialectical Behavior Therapy for Self-Harm and Suicidal Behavior in Youth: A Pilot Study · NA · not yet recruiting
- NCT07450092 — Prehospital Use of Forced Air Warming · NA · enrolling by invitation
- NCT07268716 — Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) a · NA · not yet recruiting
- NCT07392697 — The Intravenous Amino Acid Therapy for Vascular Rigidity in End Stage Renal Disease · NA · not yet recruiting
- NCT07304219 — Physical Activity Based Treatment for Youth With Depression and Anxiety · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02755714 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Haukeland University Hospital
- Last refreshed: 19 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02755714.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing