Who is sponsoring NCT02753517?

NCT02753517 is sponsored by University Hospital, Lille.

What drugs are being tested in NCT02753517?

Interventions in NCT02753517: Hepatobiliary scintigraphy.

What condition does NCT02753517 study?

NCT02753517 studies Hepatic Insufficiency.

Is NCT02753517 still recruiting?

NCT02753517 is currently terminated. Last updated 15 April 2025.

Last reviewed 2025-04-15 · How we verify

NCT02753517: SCINTIVOL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies

Terminated NA Last updated 15 April 2025

What this trial tests

NA trial testing Hepatobiliary scintigraphy in Hepatic Insufficiency in 326 participants. Terminated before completion.

Timeline

8 December 2015

Primary endpoint
10 December 2021

10 December 2021

Quick facts

Lead sponsor	University Hospital, Lille
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	screening
Enrollment	326
Start date	8 December 2015
Primary completion	10 December 2021
Estimated completion	10 December 2021
Sites	12 locations across France

Drugs / interventions tested

Hepatobiliary scintigraphy

Conditions studied

Hepatic Insufficiency — all drugs for Hepatic Insufficiency →

Sponsor

University Hospital, Lille

Who can join

18 and older, any sex, with Hepatic Insufficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Extended hepatectomies of 4 or more segments are complicated by high rates of morbidity and mortality, mainly related to hepatic liver failure. Nowadays, preoperative assessment of the future remnant liver is just performed through its volumetric measurement by computed tomography. Nevertheless, this volumetric assessment does not reflect the hepatocellular function of the future remnant liver that can be disturbed in case of vascular and/or biliary obstruction, chemotherapy-induced liver injuries or steatosis in overweight patients. Literature data (albeit originating from a single centre in Europe) have suggested that (99m)Tc-mebrofenin hepatobiliary scintigraphy could be useful in evaluating the function of the future remnant liver. The aim of this prospective multicentric study is to determine the predictive value of hepatobiliary scintigraphy in assessing the risk of postoperative liver failure of extended hepatectomies of 4 or more segments in noncirrhotic liver.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Liver Functional Volumetry by Tc-99m Mebrofenin Hepatobiliary Scintigraphy before Major Liver Resection: A Game Changer.
Gupta M, Gupta M, Choudhury PS, Singh S, et al · · 2018 · cited 24× · PMID 30386047 · DOI 10.4103/ijnm.ijnm_72_18

Verify or expand the search:

Other recruiting trials for Hepatic Insufficiency

Currently open trials in the same condition.

NCT06957756 — A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems · Phase 1 · recruiting

Other University Hospital, Lille trials

Trials by the same sponsor.

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NCT07408999 — Totally Versus Hybrid Minimally Invasive Esophagectomy for Esophageal Cancer · NA · not yet recruiting
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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02753517 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Lille
Last refreshed: 15 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02753517.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing